Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Org Lett ; 13(9): 2228-31, 2011 May 06.
Article in English | MEDLINE | ID: mdl-21446687

ABSTRACT

An NHC-catalyzed, regio- and stereoselective oxidative cyclization of o-alkynylbenzaldehydes bearing an unactivated alkyne moiety as an internal electrophile has been developed to afford phthalides and isocoumarins. A single organocatalytic system enabled two sequential C-O bond formations to take place in an atom economical manner via highly efficient dual activation. Molecular oxygen in air could be utilized as a source of an oxygen atom for the oxidation of aldehydes to the corresponding benzoic acids under our newly developed reagent system.


Subject(s)
Alkynes/chemistry , Benzaldehydes/chemistry , Heterocyclic Compounds, 2-Ring/chemical synthesis , Catalysis , Cyclization , Molecular Structure , Oxidation-Reduction
SELECTION OF CITATIONS
SEARCH DETAIL
...