[The use of the latissimus dorsi myocutaneous island flap for the reconstruction of the oral cavity floor and of the pharynx]. / Zastosowanie wyspowego plata skórno-miesniowego z m. najszerszego grzbietu w rekonstrukcji dna jamy ustnej i gardla.

The use of myocutaneous island flaps for the reconstruction of the extensive postoperative defects, enlarged possibilities of surgery treatment of malignant tumors. The report presented a case of recurrence of the tongue cancer after radiotherapy. There was performed an extensive surgery in result of which the tongue, the oral cavity floor, the pharynx and the larynx were excised. The defect was reconstructed with the latissimus dorsi myocutaneous island flap. The authors present the vascularization of the flap and the technique of its formation. The latissimus dorsi myocutaneous island flap is often used in the reconstruction of the oral cavity and the pharynx due to its long pedicle and rich vascularization.

[Investigation of variability in the vascularity of trapezius musculo-cutaneous flaps]. / Badanie zmiennosci unaczynienia skórno-miesniowych platów z miesnia czworobocznego.

The search on the human body cadavers was done to determine the exact localization of the various cutaneous island flaps depending on the course of the blood vessels. The latex solution stained with the prussian blue was injected directly into the thyro-cervical trunk or subclavian arteries. Afterwards the island musculocutaneous flaps from various regions of the trapezius muscle were performed. The whole number of the performed flaps were 20. The search confirmed the possibility of formation island flaps from various regions of the trapezius muscle.

Post resuscitation iron delocalization and malondialdehyde production in the brain following prolonged cardiac arrest.

Assays for brain tissue malondialdehyde (MDA) and low molecular weight chelated (LMWC) iron were used to examine samples of the cerebral cortex obtained from dogs 2 h after resuscitation from a 15-min cardiac arrest. The effect of post-resuscitation treatment with lidoflazine and/or desferrioxamine was similarly examined. Non-ischemic brain samples had LMWC iron levels (in nmol/100 mg tissue) of 12.32 + 2.60 and MDA levels (in nmol/100 mg tissue) of 8.46 + 1.35. Animals subjected to cardiac arrest and resuscitation and standard intensive care (SIC) had LMWC iron levels of 37.04 + 4.58 (p less than .01 against non-ischemic controls) and MDA levels of 12.24 + 1.9 (p less than .05 against non-ischemic controls). All treatment interventions significantly reduced the LMWC iron (p less than .05), but only treatment with desferrioxamine alone significantly reduced MDA (p less than .05), although a trend toward reduction of the MDA was also evident in animals treated with both desferrioxamine and lidoflazine. LMWC iron levels are increased in the post-ischemic brain, and this increase may be related to lipid peroxidation in the brain following resuscitation from cardiac arrest. These changes are probably pathologic and are amenable to pharmacologic intervention.

Perfusion of the cerebral cortex by use of abdominal counterpulsation during cardiopulmonary resuscitation.

Perfusion of the cerebral cortex (rCCBF) during resuscitation from cardiac arrest was studied using 24 large dogs and three different resuscitation models. Conventional cardiopulmonary resuscitation (CPR) was compared with interposed abdominal compression CPR (IAC-CPR) and with IAC-CPR together with infusion of epinephrine. Conventional CPR produced a mean rCCBF of only 11% (0.057 +/- 0.07 ml/min/g) normal perfusion (0.54 +/- 0.14 ml/min/g). Even without epinephrine, IAC-CPR produced mean rCCBF equal to 51% (0.27 +/- 0.17 ml/min/g) of normal. With epinephrine, IAC-CPR produced rCCBF (0.93 +/- 0.49 ml/min/g) statistically indistinguishable from normal. Both models of IAC-CPR were significantly superior to conventional CPR in perfusion of the cerebral cortex.