ABSTRACT
OBJECTIVE: To study the changes of tear film after short-term overnight orthokeratology wearing in adult myope. METHODS: Fifty adult myope aged 18 to 38 years old were enrolled in this study. The patients wore orthokeratology 6-10 h every night during this study. Data such as non-invasive tear break-up time (NITBUT), fluorescent tear break-up time (FTBUT), lower tear meniscus height (LTMH), corneal fluorescent staining as well as ocular surface disease index (OSDI) questionnaire score were measured at baseline, 1 d, 7 d, 14 d, 30 d and 90 d. RESULTS: Forty-four subjects completed the follow-up study. Tear break-up time (TBUT) decreased and became stable at 14 d after overnight orthokeratology wearing. LTMH sustained decreased and there was a difference after 90 d overnight wearing ï¼ P<0.05ï¼. Compared with baseline, the grade of corneal staining increased at all time points ï¼ P<0.05ï¼. As for the OSDI score, there was no difference at all time points. CONCLUSION: After overnight orthokeratology wearing, tear film stability and tear secretion decreased. Adult myope seems easily to suffer corneal injury after overnight orthokeratology wearing.
