ABSTRACT
BACKGROUND: Melanocytic tumours are derived from melanocytes and are common in older dogs with dark pigmented skin. Primary congenital cutaneous melanoma has been described in domestic mammals although there are no reports in the dog. HYPOTHESIS/OBJECTIVE: We describe a case of canine congenital cutaneous melanoma with rapid progression to metastasis and death. ANIMAL: A male, mixed breed dog was born with a circular ulcerated lesion near the left ear. By 12 days of age the lesion had grown significantly, with multiple soft, round nodules located at the outer base of the ear. METHODS AND RESULTS: Histopathological examination showed the proliferation of round and elongated neoplastic cells with eosinophilic cytoplasm that occasionally contained granules of melanin. Immunohistochemical analysis was positive for melan A, S-100 protein, neuron-specific enolase (NSE) and vimentin, confirming the diagnosis of melanoma. The tumour progressed rapidly and at six months the dog died suddenly. Postmortem examination revealed pulmonary, cardiac and lymph node metastases. CONCLUSIONS AND CLINICAL IMPORTANCE: To the best of the authors' knowledge, this is the first report of a primary congenital melanoma in the dog. The neoplastic condition showed malignant behaviour and high metastatic potential.
Subject(s)
Dog Diseases/congenital , Melanoma/veterinary , Skin Neoplasms/veterinary , Animals , Dog Diseases/pathology , Dogs , Fatal Outcome , Male , Melanoma/congenital , Melanoma/pathology , Skin Neoplasms/congenital , Skin Neoplasms/pathologyABSTRACT
Foi atendido no Hospital de Clínicas Veterinárias (HCV) da UFRGS um felino, macho, sem raça definida, dois anos de idade, com histórico de duas obstruções urinárias anteriores. No dia anterior foram realizadas inúmeras tentativas de sondagem, sem sucesso, em outro estabelecimento veterinário e o paciente foi, portanto, encaminhado para o HCV. No momento da consulta o paciente apresentava hiporexia, disúria e incontinência urinária. Ao exame clínico, observou-se aumento de volume em região perineal de consistência firme. Foi iniciada fluidoterapia e o animal foi anestesiado para nova tentativa de sondagem uretral. Verificou-se que não era possível a sondagem, pois a uretra peniana apresentava-se com estenose severa.
Subject(s)
Male , Animals , Cats , Urethral Obstruction/surgery , Urethral Obstruction/veterinary , Urethra/physiopathology , Urinary Catheterization/veterinary , Penis/injuriesABSTRACT
Foi atendido no Hospital de Clínicas Veterinária da UFRGS um canino da raça Pitbull, de aproximadamente cinco anos e pesando 40 kg. O animal apresentava evisceração de diversos órgãos abdominais devido a atropelamento, além de choque hipovolêmico.
