Tratamento cosmético com OnabotulinumtoxinA (Botox®): relação entre avaliação clínica inicial, dosagem e custos / Cosmetic treatment with OnabotulinumtoxinA (Botox®): relationship between initial clinical assessment, dosage and costs

Objetivo: O objetivo deste trabalho é demonstrar como a correta avaliação clínica pode influenciar na dosagem utilizada no tratamento cosmético de onabotulinumtoxinA (Botox®, Allergan, Inc, Dublin, UK) e sua consequente relação com custo e valor do tratamento a longo prazo. Método: Foram selecionados quatro pacientes para tratamento cosmético com Toxina Botulínica tipo A. Foi realizado registro fotográfico pré-procedimento, com 15 dias pós-procedimento; 3, 4, 7 e 10 meses pós-procedimento. A avaliação inicial dos pacientes, a técnica, objetivo e as dosagens utilizadas foram comentadas pelo médico que efetuou o tratamento. A avaliação e os comentários das fotos pós-procedimentos foram realizados por outro médico especialista. Resultados: Todos os pacientes tiveram as regiões frontal, glabelar e peri-orbital tratadas. As doses totais utilizadas em cada paciente foram: paciente 1: 64U; paciente 2: 69U; paciente 3: 78U e paciente 4: 81U. Conclusões: A correta avaliação clínica é fundamental para o adequado planejamento do tratamento cosmético com Botox®. Resultados duradouros, que geram alta satisfação aos pacientes, estão associados à correta escolha das doses. O custo do tratamento cosmético de Botox® deve ser avaliado de forma global e a longo prazo.

Objective: The aim of this study is to demonstrate how the correct clinical assessment can influence the dosage used in the cosmetic treatment with onabotulinumtoxinA (Botox®, Allergan, Inc., Dublin, UK) and its consequent relationship to cost and value of long-term treatment. Method: Four patients were selected for cosmetic treatment with Botulinum Toxin Type A. Patients` pictures were taken pre procedure, 15 days post procedure, 3, 4, 7 and 10 months post procedure. The patient initial evaluation, technique, objective and dosages used were commented by the doctor who performed the treatment. Evaluation and comments of the pictures post procedure were performed by another medical specialist. Results: All patients had the frontal, glabellar, and periorbital areas treated. Total doses used for each patient were as follows: patient 1: 64U; patient 2: 69U; patient 3: 78U and patient 4: 81U. Conclusions: The correct clinical assessment is essential for proper planning of cosmetic treatment with Botox®. Long lasting results, with high satisfaction rates among patients, are associated with the correct choice of doses. The cost of Botox® cosmetic treatment should be evaluated comprehensively and in a long term manner.

Sexualidade de mulheres mastectomizadas e submetidas à reconstrução mamária / Sexuality of women that suffered mastectomy and those who had been submitted to the mammary reconstruction

Objetivo: O objetivo deste estudo é avaliar, por meio do questionário FSFI (Female Function Sexual Index), e comparar a sexualidade de mulheres mastectomizadas e de mulheres que se submeteram à reconstrução mamária pós-tratamento do câncer de mama. Métodos: Foi realizado um estudo descritivo transversal. A casuística foi composta por dois grupos, um com 17 mulheres mastectomizadas e outro com 19 mulheres submetidas à reconstrução mamária pós-mastectomia, com idades entre 18 e 60 anos. Os critérios de exclusão foram: analfabetismo, vigência de tratamento de quimioterapia, radioterapia ou psiquiátrico e o tratamento cirúrgico a menos de um ano. Todas elas são pacientes dos ambulatórios de cirurgia plástica ou de mastologia da Universidade Federal de São Paulo. As voluntárias responderam ao questionário FSFI. A analise estatística foi realizada aplicando-se o teste t de Student e o coeficiente de correlação de Pearson, tendo sido adotado o nível de significância de p ≤ 0,05. Resultados: Os escores obtidos das respostas das mulheres mastectomizadas foram significativamente menores que os das submetidas à reconstrução (médias: 10,15 ± 2,636 e 22,44 ±3,055, respectivamente; p = 0,0057). Não foram observadas correlações entre os escores e o tempo de pós-operatório (pós - p = 0,9382; pré - p = 0,2142), assim como para o desenvolvimento de atividade remunerada (pós - p = 0,7699; pré – p = 0,5245), relação estável (pós - p = 0,2613; pré - p = 0,5245) e idade (pós - p = 0,3951; pré – p = 0,8427) entre os dois grupos. A idade média das pacientes não teve diferença significativa (p = 0,4740; media pós = 47,71 ± 2,012; media pré = 46,69 ± 1,809). Conclusão: Existe melhora da função sexual das pacientes mastectomizadas após a reconstrução mamária.

Objectives: The purpose of this study is to evaluate, through the FSFI (Female Function Sexual Index) questionnaire, and to compare the sexuality of women that suffered mastectomy and those who had been submitted to the mammary reconstruction post-treatment of breast cancer. Methods: A transversal descriptive study was carried out. The casuistic was composed by two groups, one with 17 women that suffered mastectomy and another with 19 submitted women to the mammary reconstruction after-mastectomy, with ages between 18 and 60 years old. The exclusion criteria were: illiteracy, use of chemotherapy, radiotherapy, psychiatric treatment, and surgical treatment in less than one year. All the patients are from the ambulatory of plastic surgery or mastology of São Paulo Federal University. The volunteers answered the FSFI questionnaire. The statistical analysis was carried out by applying the Student's t-test and Pearson's correlation coefficient, p ≤ 0.05 was taken as the significance level. Results: The scores obtained from the answers of women that suffered mastectomy were significantly lower than those from women submitted to reconstruction (means: 10.15 ± 2.636 and 22.44 ± 3.055, respectively; p = 0.0057). Correlations were not found between scores and postoperative time (post - p = 0.9382; pre - p = 0.2142) ,as well as for the development of paid activity (post - p = 0.7699; pre - p = 0.5245), stable relation (post - p = 0.2613; pre - p = 0.5245), and age (post - p = 0.3951; pre - p = 0.8427) between both groups. The mean age of the patients did not have a significant difference (p = 0.4740; post mean = 4771 ± 2.012; pre mean = 46.69 ± 1.809). Conclusion: There is an improvement of the sexual function in patients that suffered mastectomy after breast reconstruction.

Magnetic resonance images and linear measurements in the surgical treatment of breast asymmetry.

BACKGROUND: Objective evaluation of breast asymmetry surgical treatment should consider not only breast shape but also breast volume. METHODS: For this study, 22 patients with primary breast asymmetry were evaluated by magnetic resonance imaging (MRI) as well as linear measurements preoperatively and 6 months postoperatively. The mean difference between the pre- and postoperative linear measurements was graduated from excellent to poor. Breast volume was estimated by MRI from axial reconstruction for three-dimensional application using the Cavalieri formula and specific software. RESULTS: A strong correlation (r = 0.817) was found between the pre- and postoperative breast volumes, as increased or decreased by the surgical procedure. Patients with less postoperative volume differences tended to have the best ratings with linear measurements. When the same surgical procedure was performed bilaterally or when only one breast was treated by surgery, greater volume symmetry was observed. CONCLUSIONS: Linear measurements and MRI are objective methods for evaluating postoperative symmetry, and when used in association, can help plastic surgeons to achieve favorable results in mammary asymmetry treatment.