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4.
Rev Med Interne ; 29(10): 830-1, 2008 Oct.
Article in French | MEDLINE | ID: mdl-18375020

ABSTRACT

A 51-year-old woman presented with crusting rhinitis, bilateral serous otitis, inflammatory arthralgias, fever, weight loss and signs of temporal arteritis. Temporal arteries were increased in size, painful, with inflammatory signs. There was microscopic hematuria and inflammatory parameters were increased. The renal function was normal. Anticytoplasmic neutrophils antibodies were detected (anti-PR3). Temporal artery biopsy did not show signs of giant cell arteritis. A diagnostic of Wegener's granulomatosis was established and steroid treatment allowed disappearance of clinical and biologic features.


Subject(s)
Arteritis/etiology , Granulomatosis with Polyangiitis/diagnosis , Temporal Arteries/pathology , Antibodies, Antineutrophil Cytoplasmic/blood , Biopsy , Female , Granulomatosis with Polyangiitis/immunology , Humans , Middle Aged
5.
J Rheumatol ; 13(4): 774-7, 1986 Aug.
Article in English | MEDLINE | ID: mdl-3464758

ABSTRACT

The relationship between gout and coronary disease is controversial. We studied the distribution of cholesterol among lipoprotein fractions separated by ultracentrifugation in a group of 29 gouty men and 34 healthy controls, matched by age, weight and serum glucose. Our results showed that patients had significantly higher serum triglycerides and cholesterol-VLDL and lower total cholesterol and cholesterol in LDL and HDL fractions. The comparison of both groups separated by weight and alcohol intake showed similar results. The cholesterol-LDL/cholesterol-HDL ratio was not significantly different between the groups. Based on these results, we conclude that our group of gouty patients may not be at greater risk of coronary disease than a similar control population.


Subject(s)
Cholesterol/blood , Gout/blood , Lipoproteins/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Cholesterol, VLDL , Coronary Disease/etiology , Gout/complications , Humans , Lipoproteins, VLDL/blood , Male , Middle Aged , Risk , Triglycerides/blood
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