Subject(s)
Edema/complications , Heavy Chain Disease/diagnosis , Paraproteinemias/complications , Renal Insufficiency/diagnosis , Aged , Diagnosis, Differential , Edema/diagnosis , Heavy Chain Disease/complications , Humans , Lower Extremity , Male , Multiple Myeloma/complications , Multiple Myeloma/diagnosis , Paraproteinemias/diagnosis , Renal Insufficiency/complicationsSubject(s)
Abdominal Pain/etiology , Adrenal Insufficiency/complications , Hemorrhage/etiology , Thrombocythemia, Essential/complications , Abdominal Pain/diagnosis , Abdominal Pain/diagnostic imaging , Acute Disease , Adrenal Insufficiency/diagnosis , Aged, 80 and over , Anti-Inflammatory Agents/administration & dosage , Anti-Inflammatory Agents/therapeutic use , Female , Fludrocortisone/administration & dosage , Fludrocortisone/therapeutic use , Hemorrhage/diagnostic imaging , Humans , Hydrocortisone/administration & dosage , Hydrocortisone/therapeutic use , Platelet Aggregation Inhibitors/therapeutic use , Radiography, Abdominal , Thrombocythemia, Essential/drug therapy , Thrombocythemia, Essential/therapy , Time Factors , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
A 51-year-old woman presented with crusting rhinitis, bilateral serous otitis, inflammatory arthralgias, fever, weight loss and signs of temporal arteritis. Temporal arteries were increased in size, painful, with inflammatory signs. There was microscopic hematuria and inflammatory parameters were increased. The renal function was normal. Anticytoplasmic neutrophils antibodies were detected (anti-PR3). Temporal artery biopsy did not show signs of giant cell arteritis. A diagnostic of Wegener's granulomatosis was established and steroid treatment allowed disappearance of clinical and biologic features.
Subject(s)
Arteritis/etiology , Granulomatosis with Polyangiitis/diagnosis , Temporal Arteries/pathology , Antibodies, Antineutrophil Cytoplasmic/blood , Biopsy , Female , Granulomatosis with Polyangiitis/immunology , Humans , Middle AgedABSTRACT
The relationship between gout and coronary disease is controversial. We studied the distribution of cholesterol among lipoprotein fractions separated by ultracentrifugation in a group of 29 gouty men and 34 healthy controls, matched by age, weight and serum glucose. Our results showed that patients had significantly higher serum triglycerides and cholesterol-VLDL and lower total cholesterol and cholesterol in LDL and HDL fractions. The comparison of both groups separated by weight and alcohol intake showed similar results. The cholesterol-LDL/cholesterol-HDL ratio was not significantly different between the groups. Based on these results, we conclude that our group of gouty patients may not be at greater risk of coronary disease than a similar control population.
Subject(s)
Cholesterol/blood , Gout/blood , Lipoproteins/blood , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Cholesterol, VLDL , Coronary Disease/etiology , Gout/complications , Humans , Lipoproteins, VLDL/blood , Male , Middle Aged , Risk , Triglycerides/bloodABSTRACT
By means of two dimensional echocardiogram we diagnosed a trans-septal migration of a pacemaker wire. The septal perforation was corroborated by EKG and radiographic studies.