[Surgical treatment of Parkinson's disease in Poland in the last century]. / Operacyjne leczenie choroby Parkinsona w Polsce w ubieglym stuleciu.

Surgery of Parkinson's disease started in the middle of the last century. At the same time this treatment was introduced in Poland. Choróbski removed Broadsman's area 4 through craniotomy. In 1961 Liszka in Kraków introduced the stereotactic procedures, thalamo- and pallidotomy. This type of surgery was soon introduced in two other neurosurgical centers. For the next several years treatment was mostly pharmacological. However, stereotactic treatment was used in patients poorly tolerating drugs. In the meantime first attempts were made at implantation of fetal substantia nigra, with good results. At the end of the century in several patients electrostimulators were implanted. In the last century all known methods of surgical treatment were applied in Poland.

Primary intraspinal cervical melanoma.

A case of primary intraspinal melanoma is presented. This is a very rarely observed lesion, as only 37 cases have been described up to now. Patient presenting with signs and symptoms of spinal cord compression after MRI and spinal angiography was operated upon. Total removal of an intraspinal cervical tumour was performed. Histopathological investigation confirmed melanoma. Subsequent radiotherapy was given. Follow up of 4 years duration showed no signs of recurrence in MRI and full motor and sensory recovery.

[Surgical outcome of temporal lobe epilepsy]. / Wyniki operacyjnego leczenia padaczki skroniowej.

Results of the surgical treatment of temporal lobe epilepsy--Authors present their own experience in the surgical treatment of temporal lobe epilepsy. 403 patients were operated upon. The age of the patients was not limited. The beginning of the epilepsy was in most cases in early childhood, however the conservative treatment was continued for a very long time, usually over 10 years. The modern diagnostic tools, especially MRI, make it possible to diagnose the temporal epileptic focus more often, than previously, especially in cases with morphological substrate. Temporal lobectomy with amygdalo-hippocampectomy was performed. The follow-up was at least 3 years after surgery. Outs of 343 patients examined in this period 175 were cured, without seizures after surgery. Next 61 patients had no more than 2 small attacks a year. So in 69% of patients the result was very good or satisfactory. The neuropsychological investigation revealed that in most patients the IQ improved. Their quality of life improved markedly according to their own opinion.

[The significance of ocular signs for early diagnosis of pituitary tumors]. / Znaczenie objawów wzrokowych dla wczesnego rozpoznania guzów przysadki mózgowej.

The aim of the study was to analyze intensified ocular symptoms of patients with diagnosed and surgically treated pituitary macroadenoma. Material from Neurosurgery Clinic of Medical University in Warsaw covering the period since 1935 was included in the study. Duration of the period from first ocular symptoms to final diagnosis as well as condition of visual organ, especially number of patients with irreversibly damaged sight (blindness, marginal vision), were evaluated. The results of the study show that still a great number of patients undergo surgical treatment too late; in the last period 36% of patients had irreversibly damaged sight. The reason was found to be partially carelessness of the patients, however in many cases it was wrong initial medical diagnosis and not performed full diagnostic examinations. The study points to the necessity of performing adequate additional tests in cases of patients with visual field narrowing or visual acuity deterioration without clearly determined other pathology.

Disorganization of cortical structure and the brain tumors.

In the course of histopathological investigation of the temporal lobe sections, selected from 63 patients treated surgically for intractable epilepsy and finally presented with primary temporal tumors, we found 12 cases expressed both neoplastic process' and developmental disorders. The temporal mass lesions consisting of neuro-glial or pure glial tumors were associated with some developmental abnormalities such as cortical dysplasia, neuronal heterotopias and additional cortical neoplastic nodules. The possible "dual pathology" concerning these lesions are discussed in this paper.

Multilobar resections in surgical treatment of medically intractable epilepsy.

UNLABELLED: MATERIAL, METHOD: Authors present the results of surgical treatment in a series of 93 patients with medically intractable epilepsy and large epileptogenic foci, in whom multilobar resections have been performed. They constituted 13% of a group of 716 patients subjected to surgery due to drug resistant epilepsy in the period 1957-1996, in the Department of Neurosurgery, Medical University of Warsaw, Poland. Patients treated with multilobar resection constituted the group, characterised by the most severe course of epilepsy, so they usually had a long seizures' history at the time of operation (more than 10 years duration of the disease in 37% of patients), albeit they were qualified to surgery at a relatively young age (mean age at the time of surgery: 16-th year of life). Trauma was the most frequent underlying aetiologic factor (perinatal trauma and other major head injury were documented in 28% and 30% of patients respectively). Morphological abnormalities of the resected brain tissue were found on pathological examination (light microscope) in 68% of patients in this series. RESULTS: Perioperative mortality was 3%. At a follow-up examination (mean follow-up period 7 years postoperatively): 30% of patients were seizure free, in 13% of patients drug discontinuation was possible. In 23% of patients less than 2-3 seizures per year occurred. So totally in 53% of patients, good result of treatment was achieved (none or only very rare seizures). In 35% of patients surgery failed to control seizures' frequency. 9% of patients were lost from follow-up evaluation. CONCLUSIONS: Multilobar resection (if acceptable from the clinical point of view) may be an effective treatment choice in patients with medically uncontrollable seizures and huge epileptogenic foci. This treatment modality may offer recovery from seizures or significant improvement to 53% of patients treated. The radical removal of epileptogenic foci, age of the patients higher than 18 year of life at the time of operation, focal character of EEG abnormalities and occurrence of only one type of seizures, were found to be good prognostic factors. On the other hand younger age of the patients operated, the presence of generalized slow waves in the interictal EEG recordings and the occurrence of various types of seizures, influenced adversely on the prognosis.