ABSTRACT
Piperacillin is a semisynthetic penicillin with a broad-spectrum: in particular it is active against Gram positive, Gram negative, aerobic and anaerobic bacteria often resistant to other antibiotics of the same group. We report a trial carried out on 38 children with severe and moderate infections treated with piperacillin. We have considered ESR, all leucocytes count and body temperature. No severe side effects have been reported. Piperacillin must be used as a first choice in pediatric age, mostly in case of mixed bacterial infections and in immunocompromised patients.
Subject(s)
Bacterial Infections/drug therapy , Piperacillin/therapeutic use , Adolescent , Child , Drug Evaluation , Female , Humans , Infant , MaleABSTRACT
We describe 6 patients with thalassaemia major who developed diabetes. Etiopathogenesis, poor metabolic control, previous transfusion and chelation regimens are discussed. Antiaggregant therapy with A.S.A. and Dipiridamole may play a role in these patients for preventing thrombotic risk.
Subject(s)
Diabetes Mellitus, Type 1/etiology , Thalassemia/complications , Arrhythmias, Cardiac/etiology , Blood Transfusion , Child, Preschool , Diabetes Mellitus, Type 1/genetics , Diabetic Angiopathies/complications , Female , Heart Failure/etiology , Humans , Infant , Intracranial Embolism and Thrombosis/etiology , Male , Thalassemia/therapyABSTRACT
Since 1978, 818 children living near an industrial source of pollution have been screened for lead poisoning. Biochemical evidences of increased lead absorption have been found in 114 cases and in 62 of them it was of such degree to guarantee further investigations. Those 62 children received a thorough neuropsychologic evaluation revealing a significant reduction of IQ, learning difficulties, poor concentration and behavioral abnormalities. We also documented an increased rate of abnormal mathafases and breaks of chromatides in children with increased lead absorption compared with age and sex matched controls.
