ABSTRACT
A patient with acquired immune deficiency syndrome (AIDS) and cryptococcal arthritis occurring in the setting of disseminated cryptococcosis is described. The literature of cryptococcal arthritis is reviewed and the association of this unusual infection with AIDS is discussed. To our knowledge, this is the first reported association between AIDS and cryptococcal arthritis.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Arthritis, Infectious/etiology , Cryptococcosis/etiology , Adult , Arthritis, Infectious/immunology , Cryptococcosis/immunology , Disease Susceptibility , Humans , MaleSubject(s)
Bone Diseases/etiology , Bursitis/etiology , Gaucher Disease/complications , Hemorrhage/etiology , Adult , Bone Diseases/diagnostic imaging , Bursitis/diagnostic imaging , Chronic Disease , Gaucher Disease/diagnostic imaging , Humans , Knee/diagnostic imaging , Male , Radionuclide Imaging , Tibia/diagnostic imagingABSTRACT
A group of 50 patients with rheumatoid arthritis (half of whom received prednisone for 12 weeks before and then during the study) participated in a double-blind trial evaluating the efficacy and safety of 3 dosages of naproxen (125, 250, and 500 mg b.i.d.). Increasing dosages of naproxen were associated with increasing levels of therapeutic response and increasing serum levels of naproxen with no evidence of toxicity. Corticosteroid patients did not exhibit the same pattern of increasing levels of efficacy. The study demonstrates a dosage-related increasing pattern of efficacy for naproxen up to 1,000 mg/day, a pattern not yet demonstrated for the other non-steroidal antinflammatory drugs.
Subject(s)
Adrenal Cortex Hormones/administration & dosage , Arthritis, Rheumatoid/drug therapy , Naproxen/administration & dosage , Adrenal Cortex Hormones/therapeutic use , Adult , Aged , Clinical Trials as Topic , Dose-Response Relationship, Drug , Double-Blind Method , Female , Humans , Male , Middle Aged , Naproxen/adverse effects , Naproxen/bloodABSTRACT
A 50-year-old woman with a 27-year history of ankylosing spondylitis developed cricoarytenoid joint arthritis that was indicated by hoarseness, sore throat, and vocal cord fixation. This unusual manifestation of ankylosing spondylitis responded to treatment with moderate doses of prednisone, but it recurred when the cortiocosteroid therapy was discontinued.
Subject(s)
Arthritis/etiology , Laryngeal Cartilages , Spondylitis, Ankylosing/complications , Arthritis/drug therapy , Female , Humans , Middle Aged , Prednisone/therapeutic use , Recurrence , Spondylitis, Ankylosing/drug therapySubject(s)
Arthritis , Adolescent , Adult , Aged , Aging , Anti-Inflammatory Agents/therapeutic use , Arthritis/diagnosis , Arthritis/rehabilitation , Arthritis/therapy , Arthritis, Infectious/diagnosis , Arthritis, Rheumatoid/drug therapy , Aspirin/therapeutic use , Child , Child, Preschool , Chondrocalcinosis/diagnosis , Connective Tissue/physiology , Exercise Therapy , Female , Gold Sodium Thiomalate/therapeutic use , Gout/diagnosis , Humans , Infant , Joint Diseases/diagnostic imaging , Joint Diseases/drug therapy , Joints/anatomy & histology , Joints/physiology , Lupus Erythematosus, Systemic/diagnosis , Male , Middle Aged , Myositis/diagnosis , Orthopedics , Polymyalgia Rheumatica/diagnosis , Radiography , Reflex Sympathetic Dystrophy/diagnosis , Scleroderma, Systemic/diagnosisABSTRACT
A patient is described with rheumatoid arthritis and a painful synovial cyst, which originated from a metatarsophalangeal joint and presented as a swelling on the plantar surface of the foot. The cyst was successfully excised.
