ABSTRACT
The "Euro-Lupus Cohort" is composed by 1000 patients with systemic lupus erythematosus (SLE) that have been followed prospectively since 1991. These patients have been gathered by a European consortium--the "Euro-Lupus Project Group". This consortium was originated as part of the network promoted by the "European Working Party on SLE", a working group created in 1990 in order to promote research in Europe on the different problems related to this disease. The "Euro-Lupus Cohort" provides an updated information on the SLE morbidity and mortality characteristics in the present decade as well as defines several clinical and immunological prognostic factors.
Subject(s)
Autoimmune Diseases/diagnosis , Autoimmune Diseases/epidemiology , Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/epidemiology , Age of Onset , Antibodies, Antinuclear/blood , Autoimmune Diseases/blood , Autoimmune Diseases/mortality , Cohort Studies , Europe/epidemiology , Female , Follow-Up Studies , Humans , Lupus Erythematosus, Systemic/blood , Lupus Erythematosus, Systemic/mortality , Male , Morbidity , Prognosis , Prospective Studies , Survival RateABSTRACT
The "Euro-Lupus Cohort" is composed by 1,000 patients with systemic lupus erythematosus (SLE) that have been followed prospectively since 1991. These patients have been gathered by a European consortium - the "Euro-Lupus Project Group". This consortium was originated as part of the network promoted by the "European Working Party on SLE", a working group created in 1990 in order to promote research in Europe on the different problems related to this disease. The "Euro-Lupus Cohort" provides an updated information on the SLE morbidity and mortality characteristics in the present decade as well as defines several clinical and immunological prognostic factors.
Subject(s)
Lupus Erythematosus, Systemic/epidemiology , Adolescent , Adult , Age of Onset , Antibodies, Antinuclear/blood , Cohort Studies , Europe/epidemiology , Female , Humans , Lupus Erythematosus, Systemic/blood , Lupus Erythematosus, Systemic/mortality , Male , Middle Aged , Prognosis , Prospective Studies , Survival RateABSTRACT
Aim. To evaluate the reasons for atypical sequelae of knee arthroscopy.
Material. A group of 11 patients (6 women and 5 men), age 17-56 (mean 33.4), referred for rheumatological consulation because of persistent exudates and/or pain in the operated joint. Infectious arthritis, rheumatoid arthritis, psoriatic arthritis and gout were excluded. Immunological diagnostics were performed on all patients, testing for the presence of anti-Chlamydia trachomatis, anti-Yersinia enterocolitica, anti-Salmonella enteritidis and typhimurium antibodies.
Results. In 10/11 patients various antibodies were detected (most often anti-Chlamydia trachomatis antibodies). Other reasons for atypical sequelae of knee arthroscopy included pigmentous villo-nodular synovitis and chondrocalcinosis. The Discussion presents those clinical symptoms and signs appearing in orthopedic examinations that serve as indications for rheumatological consultation.
Conclusion. The most common reason for atypical sequelae of knee arthroscopy is reactive arthritis caused by Chlamydia trachomatis and G(-) enteric bacteria infections.
