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2.
Ann Biomed Eng ; 49(11): 3018-3030, 2021 Nov.
Article in English | MEDLINE | ID: mdl-34297262

ABSTRACT

Modern changes in warfare have shown an increased incidence of lumbar spine injuries caused by underbody blast events. The susceptibility of the lumbar spine during these scenarios could be exacerbated by coupled moments that act with the rapid compressive force depending on the occupant's seated posture. In this study, a combined loading lumbar spine vertebral body fracture injury criteria (Lic) across a range of postures was established from 75 tests performed on instrumented cadaveric lumbar spine specimens. The spines were predominantly exposed to axial compressive forces from an upward vertical thrust with 64 of the tests resulting in at least one vertebral body fracture and 11 in no vertebral body injury. The proposed Lic utilizes a recommended metric (κ), based on prismatic beam failure theory, resulting from the combination of the T12-L1 resultant sagittal force and the decorrelated bending moment with optimized critical values of Fr,crit = 5824 N and My,crit = 1155 Nm. The 50% risk of lumbar spine injury corresponded to a combined metric of 1, with the risk decreasing with the combined metric value. At 50% injury risk the Normalized Confidence Interval Size improved from 0.24 of a force-based injury reference curve to 0.17 for the combined loading metric.


Subject(s)
Blast Injuries , Fractures, Bone , Lumbar Vertebrae/injuries , Spinal Injuries , Aged , Explosions , Humans , Male , Middle Aged , Stress, Mechanical
3.
J Biomech ; 92: 162-168, 2019 Jul 19.
Article in English | MEDLINE | ID: mdl-31164224

ABSTRACT

Post-mortem human subjects (PMHS) are frequently used to characterize biomechanical response and injury tolerance of humans to various types of loading by means of instrumentation installed directly on the skeleton. Data extracted from such tests are often used to develop and validate anthropomorphic test devices (ATDs), which function as human surrogates in tests for injury assessment. Given that the location and orientation of installed instrumentation differs between subjects, nominally similar measurements made on different PMHS must be transformed to standardized, skeletal-based local coordinate systems (LCS) before appropriate data comparisons can be made. Standardized PMHS LCS that correspond to ATD instrumentation locations and orientations have not previously been published. This paper introduces anatomically-defined PMHS LCS for body regions in which kinematic measurements are made using ATDs. These LCS include the head, sternum, single vertebrae, pelvis, femurs (distal and proximal), and tibiae (distal and proximal) based upon skeletal landmarks extracted from whole body CT scans. The proposed LCS provide a means to standardize the reporting of PMHS data, and facilitate both the comparison of PMHS impact data across institutions and the application of PMHS data to the development and validation of ATDs.


Subject(s)
Bone and Bones/anatomy & histology , Head/anatomy & histology , Biomechanical Phenomena , Bone and Bones/diagnostic imaging , Bone and Bones/physiology , Cadaver , Head/diagnostic imaging , Head/physiology , Humans , Tomography, X-Ray Computed , Wounds and Injuries/physiopathology
4.
J Cataract Refract Surg ; 31(6): 1238-41, 2005 Jun.
Article in English | MEDLINE | ID: mdl-16039504

ABSTRACT

Laser in situ keratomileusis (LASIK) is a common and popular procedure that is generally associated with excellent results and few complications. We present 3 cases of unusual LASIK-related complications. In the first case, the patient developed anisocoria after otherwise unremarkable surgery. In the second case, the patient developed mild eyelid ptosis. In the third case, the patient's exotropia resolved after mild refractive overcorrection. In each case, the visual outcome was excellent and no further intervention was necessary.


Subject(s)
Anisocoria/etiology , Astigmatism/surgery , Blepharoptosis/etiology , Exotropia/therapy , Keratomileusis, Laser In Situ/adverse effects , Lasers, Excimer , Myopia/surgery , Adult , Anisocoria/diagnosis , Blepharoptosis/diagnosis , Exotropia/physiopathology , Female , Humans , Male , Visual Acuity/physiology
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