1.
Org Biomol Chem
; 13(14): 4289-95, 2015 Apr 14.
Article
in English
| MEDLINE
| ID: mdl-25758157
ABSTRACT
PPA-induced umpolung triggers efficient nucleophilic addition of unactivated anilines to nitroalkanes to produce N-hydroxyimidamides. The latter undergo sequential acid-promoted cyclocondensation with ortho-OH or ortho-NHR moieties to afford benzoxazoles and benzimidazoles, respectively.
Subject(s)
Alkanes/chemistry , Aniline Compounds/chemistry , Benzimidazoles/chemistry , Benzoxazoles/chemistry , Nitro Compounds/chemistry , Phosphoric Acids/chemistry , Polymers/chemistry
2.
Org Biomol Chem
; 12(48): 9786-8, 2014 Dec 28.
Article
in English
| MEDLINE
| ID: mdl-25371015
ABSTRACT
A modular approach to 3-substituted 2-quinolones via a cascade annulation reaction between 4-nitroketones and hydrazines has been developed.
