Sleep and critical care.

PURPOSE OF REVIEW: Sleep distortion has been studied as an independent risk factor for morbidity and mortality; however, this role in the ICU patients is unclear. These patients suffer from psychological and physiological stressors and significant disturbance in sleep. We conducted a systematic review of all recent data over the last decade to elaborate the extent and implications of sleep disruption in the ICU. RECENT FINDINGS: Despite adequate data proving that ICU patients have poor quality of sleep over the last three decades, the implications of the sleep distortion in this patient population remains misunderstood. Recently, the Whitehall cohort trial has raised interest in sleep and mortality and substantial data have surfaced regarding prevalence of sleep disturbance in the ICU. SUMMARY: This article discusses the available data on sleep disruption in patients in the ICU and implications with discussion of effects of ventilators and commonly used medications in the ICU. We will conclude with interventions to improve sleep in the intensive care setting.

Identification and treatment of bronchoconstriction induced by a vagus nerve stimulator employed for management of seizure disorder.

We evaluated a 63-year-old woman who developed dyspnea with a sensation of chest tightness that was temporally associated with discharges from a vagus nerve stimulator that had been implanted for the control of intractable seizures. Spirometry demonstrated the development of significant airflow obstruction associated with the firing of the stimulator. Adjustment of the stimulator settings resolved the discharge-associated bronchoconstrictive phenomenon. These findings highlight an important association between vagus nerve stimulators and dyspnea that should be considered in the differential diagnosis of patients with these devices who present with dyspnea and/or chest tightness. The relative importance of vagal stimulation to bronchoconstriction is suggested by the findings.

Shifting care of chronic ventilator-dependent patients from the intensive care unit to the nursing home.

BACKGROUND: Among the most resource intensive and challenging of medical needs is the treatment of patients requiring long-term or chronic mechanical ventilation. Expenditures are significant, and definitions of "successful weaning," are often inconsistent. A weaning program was initiated for patients referred to a stand-alone nursing home ventilator unit. METHODS: Weaning entailed standardized weaning protocols, enhanced socialization, a multidisciplinary approach to care, empowerment of staff to initiate weaning, and aggressive utilization of noninvasive positive pressure ventilation (NPPV) in selected patients. RESULTS: Sixty-eight (67%) of 102 patients were successfully weaned during a six-year period. NPPV facilitated successful weaning in 27 (26%) of 102 patients. Of the 28 chronic ventilator-dependent patients admitted with a neuromuscular etiology for respiratory failure, NPPV was utilized in 73% (8/11) of the successfully weaned patients. Total variable costs per ventilator per patient per day for the years 1998-2000 were $319.79, $302.75, and $297.59. Six-year cost savings for referring hospitals were estimated at $18.5 million. DISCUSSION: Incentives were aligned between the hospital, nursing home, and physicians to develop a financially stable model. Developing an off-site nursing home ventilator unit resulted in significant cost savings to the referring hospitals and positively affected patient flow.