[The effect of dispersed silicon dioxide--aerosil A-300--on the growth of Saccharomyces cerevisiae yeasts]. / Vliianie dispersnogo dioksida kremniia--aérosila A-300 na rost drozhzhei Saccharomyces cerevisiae.

High-dispersed silicon dioxide--aerosil A-300 has been studied for its effect on the growth of yeast Saccharomyces cerevisiae. It is shown that at heterophase cultivation of these microorganisms under periodical conditions introduction of aerosil A-300 induces a decrease of the lag phase duration and an increase of the maximum specific growth rate and economic coefficient of the carbon substrate utilization. This high-dispersed material has exerted the similar effect under the conditions of chemostatic cultivation. Optimal parameters of this process are determined.

[Changes in the proliferative activity of cells from lymphoid organs of tumor-bearing mice after immunization with antitumoral vaccines]. / Izmeneniia proliferativnoi aktivnosti kletok limfoidnykh organov myshei s opukhol'iu pri immunizatsii protivoopukholevymi vaktsinami.

The level of proliferative activity is studied in the cells of thymus, spleen and lymphoid nodes of mice with transplanted OH-2 tumour once- or thrice-immunized with vaccines from syngeneic tumour cells. Single immunization is shown to induce the short-term modulation of the proliferative processes in lymphoid organs and to increase somewhat the level of antitumour resistance of vaccinized mice. The triple-inoculation of vaccines evokes a more pronounced rise in the level of the proliferative activity in cells of lymphoid organs.

[The effect of antitumor vaccine on the recurrence of solid tumors in mice subjected to surgery]. / Vliianie protivoopukholevoi vaktsiny na retsidivirovanie solidnykh novoobrazovanii u prooperirovannykh myshei.

The frequency of tumour recurrences in A/Sn mice with operated Ehrlich carcinomas and treated with lyophylized antitumour vaccine and trypan blue or both of them was investigated. The tumours in vaccinated mice relapsed by the 47th day after the operation in 10% of cases, in 50% of control animals, the injection of trypan blue increased the tumour recurrences by 20%. The antitumour effect of vaccination is associated with the enhancement of the activity of the cellular and humoral immune systems. The trypan blue inhibition of the macrophage function suppresses the antitumor activity of the immunity cellular components.