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Poumon Coeur ; 35(2): 105-9, 1979.
Article in French | MEDLINE | ID: mdl-471872

ABSTRACT

Mucormycoses are rare, acute infections, most often fatal, occurring usually in a host with decreased immunity. The agents are ubiquitous fungi belonging to the Mucoraceae family, an ordinary saprophyte becoming pathogenous in patients with a severe disease (malignant hemopathy, diabetes) or treated by immunosuppressive drugs. Pulmonary localizations remained exceptional (128 cases found in the literature). The observations reported draws its originality from: -- the etiological circumstances: an aged patient with no hemopathy or diabetes, without immunosuppressive treatment but undergoing a prolonged antibiotic therapy; -- the clinical signs: discovery on X-ray of excavated infiltrates in a background of a severe infection with a very poor physical condition; -- the diagnosis criteria with the demonstration of the responsible mucor in the sputum, the endobronchial aspiration and transparietal puncture; -- the great efficiency of Amphotericin B at rather small doses. A review of the literature underlines the exceptional character of the cure.


Subject(s)
Lung Diseases, Fungal/diagnosis , Mucormycosis/diagnosis , Aged , Amphotericin B/therapeutic use , Humans , Lung Diseases, Fungal/drug therapy , Lung Diseases, Fungal/immunology , Male , Mucormycosis/drug therapy , Mucormycosis/immunology
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