[Urothelial neoplasia as a late complication of transitional-cell carcinoma of the bladder]. / La neoplasia uroteliale come complicanza tardiva del carcinoma transizionale della vescica.

We evaluated the long term incidence of lower urinary tract neoplasms in patients with primary transitional bladder carcinoma. 8 patients had lower urinary tract neoplasm after a median elapse of time of 44 months (range 28 to 70). In 5 patients wa present vesicoureteral reflux. All the patients were undergone trial of BCG after the first recurrence of bladder carcinoma. We suppose that the vesicoureteral reflux may be the possible cause of ureteral neoplasm onset. Because of patients with primary bladder tumors are at the risk for lower urinary tract neoplasm, we suggest the need regular and continuous monitoring in case of frequent recurrence of transitional cell carcinoma of the bladder.