Subject(s)
Plant Poisoning/veterinary , Plants, Toxic , Sheep Diseases/etiology , Animals , Depression/etiology , Diarrhea/etiology , Diarrhea/veterinary , Kidney/pathology , Kidney Tubular Necrosis, Acute/etiology , Kidney Tubular Necrosis, Acute/pathology , Kidney Tubular Necrosis, Acute/veterinary , Plant Poisoning/etiology , Plant Poisoning/mortality , Sheep , Sheep Diseases/mortalityABSTRACT
A 4-fold or greater seroconversion to the snowshoe hare serotype of the California serogroup of viruses in a horse with acute encephalitis was demonstrated by hemagglutination-inhibition, complement-fixation, and neutralization tests. The horse had a mild fever, was ataxic, had a head tilt, and was observed to circle. Chloramphenicol, dexamethasone, and B complex vitamins were administered and the horse recovered. The snowshoe hare virus is a recognized human pathogen, but it has not been associated with disease in horses. It is unknown whether horses play a role as amplification hosts for the snowshoe hare virus in nature, and further studies appear indicated.
Subject(s)
Antibodies, Viral/analysis , Bunyaviridae/immunology , Encephalitis Virus, California/immunology , Encephalitis, Arbovirus/veterinary , Encephalitis, California/veterinary , Horse Diseases/diagnosis , Animals , Complement Fixation Tests/veterinary , Encephalitis, California/diagnosis , Hemagglutination Inhibition Tests/veterinary , Horses , Male , Neutralization TestsABSTRACT
An outbreak of central nervous system disease affecting young pigs occurred in the fall of 1981 in eastern Ontario. A diagnosis of viral encephalomyelitis was made on pathological grounds and virus isolation studies were subsequently initiated to determine the causative agent. Cultural isolation procedures using several biological systems failed to detect virus in nervous tissues from affected animals. Direct extraction of similar tissues by combined biochemical and biophysical procedures yielded nonenveloped , spherical particles with a diameter of 30 nm and a buoyant density of 1.34 g/mL in CsCl. A tentative diagnosis of enterovirus infection was made on this basis.
