ABSTRACT
OBJECTIVES: The aim of this study is to assess magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), T2-weighted image (T2WI), and apparent diffusion coefficient (ADC) maps' threshold values before computed tomography (CT)-guided transthorasic biopsy in solitary pulmonary nodules (SPN) by describing tumoral cell density. MATERIALS AND METHODS: Patients who had SPN were prospectively evaluated with MRI (T1WI, T2WI) and DWI (b=0, b=500, b=1000).The ADC maps were created for each patient. Before the biopsy, lesion muscle ratios (LMR) at T2WI, ADC value, and lesion spinal cord ratio at each b values were noted. The measurements were correlated with the histopathological results. RESULTS: A total of 53 patients were included in the study: 30.2% (n=16) were female, and 69.8% (n=37) were male. Among them, 17 lesions (32.1%) were benign, and 36 lesions (67.9%) were malignant. The age varied between 40 and 82 years, with a mean of 61.7±9.1 years. The SPN diameters were between 10 and 30 mm, and the median was 24 mm. The LSR0 and LMR values were not statistically significant in detecting malignancy. LSR500 >0.53 value can predict malignancy with 100% sensitivity and 70.6% specificity. LSR1000 >0.53 can predict malignancy with 88.9% sensitivity and 88.2% specificity. Setting the cut-off value at 0.9×10-3, the ADC values had a sensitivity of 72.2% and a specificity of 88.2% for predicting malignancy. CONCLUSION: For SPN follow-up, a new following-up protocol can be safely established using DWI and ADC mapping. Using these MRI parameters might decrease unnecessary biopsy rates and complications of biopsies.
ABSTRACT
PURPOSE: The techniques mostly used for the diagnosis of superior mesenteric artery (SMA) stenosis are computed tomography angiography (CTA), and magnetic resonance angiography. We aimed to evaluate color-coded Doppler Ultrasonography (CDUS) for the detection of SMA stenoses and to determine Doppler criteria. METHODS: We identified retrospectively 65 patients with CTA images of SMA stenosis and examined them with CDUS for the Doppler measurement of SMA peak systolic flow velocity (PSV), end-diastolic velocity (EDV), and mesenterico-aortic ratio (MAR). Results were analyzed with receiver-operating characteristic curve analysis. RESULTS: The optimal threshold values for determining 50%-69% SMA stenoses were PSV >280 cm/s, EDV >45 cm/s, and MAR >3.6. For identifying 70%-99% SMA stenoses, they were PSV >395 cm/s, EDV >74 cm/s, and MAR >3.6. CONCLUSION: CDUS is a convenient method with high accuracy for identifying SMA stenosis. PSV yielded better results than EDV and MAR.
Subject(s)
Mesenteric Artery, Superior/diagnostic imaging , Mesenteric Vascular Occlusion/diagnostic imaging , Ultrasonography, Doppler, Color , Adult , Aged , Aged, 80 and over , Blood Flow Velocity , Computed Tomography Angiography , Constriction, Pathologic , Female , Humans , Male , Mesenteric Artery, Superior/physiopathology , Mesenteric Vascular Occlusion/physiopathology , Middle Aged , ROC Curve , Retrospective StudiesABSTRACT
Background Video-assisted thoracic surgery (VATS) is widely used for thoracic surgery operations, and day by day it becomes routine for the excision of undetermined pulmonary nodules. However, it is sometimes hard to reach millimetric nodules through a VATS incision. Therefore, some additional techniques were developed to reach such nodules little in size and which are settled on a challenging localization. In the literature, coils, hook wires, methylene blue, lipidol, and barium staining, and also ultrasound guidance were described for this aim. Herein we discuss our experience with CT-guided methylene blue labeling of small, deeply located pulmonary nodules just before VATS excision. Method From April 2013 to October 2016, 11 patients with millimetric pulmonary nodules (average 8, 7 mm) were evaluated in our clinic. For all these patients who had strong predisposing factors for malignancy, an 18F-FDG PET-CT scan was also performed. The patients whose nodules were decided to be excised were consulted the radiology clinic. The favorable patients were taken to CT room 2 hours prior to the operation, and CT-guided methylene blue staining were performed under sterile conditions. Results Mean nodule size of 11 patients was 8.7 mm (6, 2-12). Mean distance from the visceral pleural surface was 12.7 mm (4-29.3). Four of the nodules were located on the left (2 upper lobes, 2 lower lobes), and seven of them were on the right (four lower lobes, two upper lobes, one middle lobe). The maximum standardized uptake values (SUV max) on 18F-FDG PET/CT scan ranged between 0 and 2, 79. Conclusion CT-guided methylene blue staining of millimetric deeply located pulmonary nodules is a safe and feasible technique that helps surgeon find these undetermined nodules by VATS technique without any need of digital palpation.
