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1.
J Forensic Sci ; 63(2): 611-613, 2018 Mar.
Article in English | MEDLINE | ID: mdl-28691733

ABSTRACT

We report the case of a middle-aged man, without medical history, who suddenly died at his workplace. The autopsy highlighted a pathological heart macroscopically, with multiple small white areas on the left myocardium. Coronary dissection revealed a pseudotumoural fibromyxoid aspect within the anterior interventricular artery (AIVA) and the left main coronary trunk, including reduction in their diameter with tight stenosis. Microscopic examination of these arteries showed fibroinflammatory wall destruction. In the left myocardium, there were multiple focal ischemic areas at different stages of recovery. Our case is an illustration of primary ischemic heart disease due to coronary arteritis, with a pseudotumoural presentation, which was revealed by sudden death. We discuss the cause of death and the etiological diagnosis preceding coronary arteritis.


Subject(s)
Arteritis/pathology , Coronary Vessels/pathology , Death, Sudden, Cardiac/etiology , Coronary Stenosis/pathology , Humans , Male , Middle Aged , Myocardial Ischemia/etiology , Myocardial Ischemia/pathology , Myocardium/pathology
2.
J Forensic Sci ; 53(2): 288-95, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18284532

ABSTRACT

Age determination is a major field of interest in physical and forensic anthropology. Among the different methods based on macroscopic skeletal study, the Iscan method, which analyzes the sternal end of the right fourth rib, is one of the most reliable. We applied the Iscan method to two- and three-dimensional multislice computed tomography (MSCT) reconstructions of the sternal end of the right fourth rib on 39 ribs. The intra-observer variability on MSCT reconstructions was good (gamma coefficient equal to 0.86; value of the Krippendorff's alpha reliability equal to 0.79); inter-observer variability on MSCT reconstructions was also good (gamma coefficient ranging from 0.82 to 0.88; value of the Krippendorff's alpha reliability ranging from 0.78 to 0.86). We demonstrated excellent agreement between the results of analysis of bone samples and those of the two- and three-dimensional images, in particular regarding bone projections, morphology of the pit and of its rim. The accuracy of age estimation did not significantly differ between the Iscan method applied to dry bones and the same method applied to MSCT images. Determination of the Krippendorff's alpha reliability coefficient for the inter-error method confirmed the agreement between phase estimations obtained with the two methods (ranging from 0.55 to 0.71). The real civil age was comprised in 21 cases out of 36 for assessment performed on dry bones and in 23 cases out of 36 on MSCT reconstructions, which represented 58.3% and 63.9%, respectively. Use of MSCT reconstructions in forensic anthropology offers many advantages: no bone preparation, no damage to bone material, and the possibility of application to living individuals.


Subject(s)
Age Determination by Skeleton/methods , Forensic Anthropology/methods , Ribs/diagnostic imaging , Adult , Female , Humans , Imaging, Three-Dimensional , Male , Middle Aged , Reproducibility of Results , Ribs/anatomy & histology , Tomography, X-Ray Computed/methods
3.
Prog Urol ; 17(4): 789-93, 2007 Jun.
Article in French | MEDLINE | ID: mdl-17633987

ABSTRACT

OBJECTIVES: To analyse technical innovations, their results and the changing legislation in France concerning sterilizing or contraceptive vas deferens surgery. MATERIAL AND METHODS: A review of the literature was performed using the key words: male/contraception/vas deferens. From the 332 research articles obtained from PUBMED, we selected 54 articles for their methodological quality and the importance of their results. RESULTS: Vasectomy remains the only validated vas deferens surgical technique. Although microsurgical reconstructive techniques have improved the vas deferens restoration rate, vasectomy must be considered to be a definitive method of sterilization. The other contraceptive (reversible) vas deferens surgical techniques have not demonstrated sufficient efficacy to be used outside of the context of clinical trials. However the encouraging results ofsome ofthese studies could allow their development in the intermediate term. From a legal point of view, since the reform of sterilizing surgery in Article L2123-1 of the French Public Health Act, vasectomy is now authorized in a regulatory framework. CONCLUSION: The urology community must take into account progress in the field of contraceptive vas deferens surgical techniques.


Subject(s)
Contraception/methods , Vas Deferens/surgery , Vasectomy/methods , France , Humans , Male , Vasectomy/legislation & jurisprudence
4.
J Forensic Sci ; 50(3): 507-12, 2005 May.
Article in English | MEDLINE | ID: mdl-15932079

ABSTRACT

Age determination is a major field of interest in forensic anthropology. Among the different methods based on macroscopic skeletal study, the Suchey-Brooks method, which analyzes the pubic symphysis, is one of the most reliable. We applied the Suchey-Brooks method to three-dimensional computed tomographic reconstructions of the pubic symphysis. We demonstrated excellent agreement between the results of analysis of bone samples and those of the three-dimensional images, in particular regarding ridges of the articular surface and delimitation of the extremities. The accuracy of age estimation did not significantly differ (Wilcoxon test) between the Suchey-Brooks method applied to bones and the same method applied to CT images. Using high-quality images, this approach seems as reliable as the standard Suchey-Brooks method and offers several advantages: no bone preparation, no damage to bone material, and the possibility of application to living individuals.


Subject(s)
Age Determination by Skeleton , Imaging, Three-Dimensional/methods , Pubic Symphysis/diagnostic imaging , Tomography, X-Ray Computed/methods , Adult , Aged , Aged, 80 and over , Algorithms , Female , Forensic Pathology/methods , France , Humans , Male , Middle Aged , Pubic Symphysis/pathology , Reproducibility of Results
5.
J Clin Forensic Med ; 10(1): 5-7, 2003 Mar.
Article in English | MEDLINE | ID: mdl-15275039

ABSTRACT

Sperm detection can be an important factor in confirming sexual assault in cases of rape. This paper compares two biochemical methods used in forensic medicine: the first detects the presence of zinc, the second detects acid phosphatase activity. The population studied was composed of 174 consenting women seen at the Male Infertility Center in Toulouse, France. The date of their last sexual intercourse was known accurately. Cytology was the reference test to confirm the presence of sperm in the vaginal samples. We studied the sensitivity, specificity, and positive and negative predictive value of the two biochemical methods. Acid phosphatase detection was the most valuable technique, but its use is limited in time. The zinc test gave disappointing results in our study and does not seem to be a useful reference method for the forensic physician.

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