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2.
Cutis ; 81(1): 33-6, 2008 Jan.
Article in English | MEDLINE | ID: mdl-18306845

ABSTRACT

An 88-year-old man from the Dominican Republic with a history of gastric adenocarcinoma was admitted with one month of fatigue, anorexia, weight loss, and abdominal pain. The dermatology department was consulted to evaluate an asymptomatic, shiny, firm, red nodule on the lower left chest, with an expanding rim of erythema. Skin biopsies were performed from the nodule and surrounding rim of erythema, which were both diagnostic of peripheral T-cell lymphoma (PTCL). This case is a unique example of PTCL with erysipelaslike spread.


Subject(s)
Lymphoma, T-Cell, Peripheral/diagnosis , Skin Neoplasms/diagnosis , Skin/pathology , Aged, 80 and over , Antigens, CD/analysis , Diagnosis, Differential , Erysipelas/diagnosis , Fatal Outcome , Humans , Immunohistochemistry , Immunophenotyping , Male
4.
J Drugs Dermatol ; 5(5): 469-72, 2006 May.
Article in English | MEDLINE | ID: mdl-16703788

ABSTRACT

Trachyonychia is the term used to describe nail plate roughness, pitting, and ridging that may affect 1 to 20 nails. Alopecia areata, psoriasis, lichen planus, atopic dermatitis, ichthyosis vulgaris, as well as other skin conditions have been associated with trachyonychia, but the causal relationship is often challenging to demonstrate histologically. Clinical evidence of these cutaneous disorders in conjunction with a nail matrix biopsy may help elucidate an etiology of trachyonychia, but many cases often remain idiopathic. Nail biopsy findings may match skin histology, but more commonly show spongiotic or nonspecific changes. We present an interesting case of a female with progressive development of trachyonychia in all 20 nails coinciding with a new diagnosis of sarcoidosis.


Subject(s)
Nail Diseases/diagnosis , Sarcoidosis/diagnosis , Biopsy, Needle , Dermatologic Agents/therapeutic use , Diagnosis, Differential , Disease Progression , Female , Follow-Up Studies , Foot Dermatoses/diagnosis , Foot Dermatoses/drug therapy , Hand Dermatoses/diagnosis , Hand Dermatoses/drug therapy , Humans , Immunohistochemistry , Middle Aged , Nail Diseases/drug therapy , Risk Assessment , Sarcoidosis/drug therapy , Severity of Illness Index
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