ABSTRACT
BACKGROUND: At present, the term mucocele is outdated, and mucinous appendiceal neoplasm is preferred. Mucinous appendiceal neoplasm is an uncommon pathology that occurs predominantly in middle-aged women. Its classification and management have been the subject of debate in recent decades. The aim of this study was to analyse the incidence, clinical management and survival of these tumours diagnosed in our centre in the last 10 years. METHODS: This was a retrospective observational study of patients with a diagnosis of appendiceal neoplasms between 2009 and 2018 in our centre. Variables such as sex, age, tumour type, clinical status, diagnosis, treatment and survival were collected. All data were analysed using the statistical program IBM SPSS Statistic® version 25. RESULTS: Twenty-nine patients with a diagnosis of appendiceal neoplasm were identified, and 24 corresponded to neoplastic appendiceal mucinous lesions (85.7%). The average age was 59.7 ± 17.6 years. Most patients were women (15 cases; 62.5%). Most of them presented with chronic abdominal pain (37.5%), and the diagnosis was performed by computed tomography (CT) (50%). The treatment was surgical in all cases. The surgical technique depended on the findings and histology of the tumour. CONCLUSION: Mucinous appendiceal neoplasms are an uncommon entity, and their pathological classification and management have recently changed.
Subject(s)
Appendiceal Neoplasms/diagnosis , Appendiceal Neoplasms/surgery , Appendix/diagnostic imaging , Mucocele/surgery , Tomography, X-Ray Computed/methods , Adult , Aged , Appendiceal Neoplasms/epidemiology , Female , Humans , Middle Aged , Mucocele/diagnostic imaging , Mucocele/epidemiology , Retrospective StudiesABSTRACT
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Subject(s)
Humans , Male , Middle Aged , Ustekinumab/adverse effects , Nephrotic Syndrome/chemically induced , Nephrotic Syndrome/diagnosis , Psoriasis/drug therapy , Ustekinumab/therapeutic useABSTRACT
Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by platelet aggregation and mechanical damage to erythrocytes, clinically characterized by microangiopatic haemolytic anemia, thrombocytopenia and organ injury. We are reporting a case of a woman patient with severe hemolytic uremic syndrome associated to infectious diarrhoea caused by Shiga toxin-producing pathogen, who were admitted to our intensive care unit. The patient described developed as organ injury, neurological failure and acute renal failure, with need of haemodialysis technique. Due to the severity of the case and the delay in the results of the additional test that help us to the final diagnose, we treated her based on a syndromic approach of TMA with plasma exchange, with favourable clinical evolution with complete recovery of organ failures. We focus on the syndromic approach of these diseases, because thrombotic thrombocytopenic purpura, one of the disorders that are included in the syndromes of TMA, is considered a haematological urgency given their high mortality without treatment; and also review the TMA in adults: Their pathogenesis, management and outcomes.
ABSTRACT
El carcinoma de los conductos colectores (CCC) es una entidad poco frecuente que representa menos del 1 por ciento del total de las neoplasias renales. La mayoría de los casos publicados han sido descritos como tumores de gran agresividad y de mal pronóstico. Presentamos un caso de un CCC de bajo grado y de pronóstico favorable al que se le realizó una nefrectomía radical sin evidencia de recidiva tumoral tras dos años de seguimiento (AU)
