ABSTRACT
We report a case of bilateral acute iris transillumination (BAIT) syndrome caused by an overdose of oral moxifloxacin in a Hispanic female patient with no previous respiratory viral infection. A 56-year-old Hispanic female with no history of ocular illness was referred to our glaucoma service to manage her microcystic edema, swelling, and refractory ocular hypertension. Her ocular and systemic symptoms, including progressively worsening bilateral ocular pain, severe photophobia, blurred vision, nausea, and vomiting, started 14 days after an accidental overdose of oral moxifloxacin. Moxifloxacin had been prescribed to treat a complicated urinary tract infection. A slit-lamp examination revealed bilateral microcystic corneal edema and transillumination in the right temporal iris, both consistent with a diagnosis of BAIT syndrome. The existing literature on BAIT syndrome is scarce, and its etiology remains unclear. This case provides clinical evidence supporting moxifloxacin toxicity as a possible cause of BAIT syndrome. We emphasize the importance of conducting extensive research to define the mechanisms involved in moxifloxacin-induced BAIT syndrome and to search for other potential etiologies of this condition.
ABSTRACT
To describe a case of transient bilateral vitreomacular traction syndrome associated with topical 1% pilocarpine ophthalmic solution in both eyes as a treatment for advanced glaucoma. Observations: Spectral-domain OCT demonstrated bilateral vitreomacular traction syndrome after initiation of topical 1% pilocarpine solution in both eyes for advanced glaucoma. Follow-up imaging revealed the resolution of vitreomacular traction after cessation of the drug without a complete posterior vitreous detachment. Conclusions and Importance: In the advent of new pilocarpine formulations, this case raises the concern of vitreomacular traction syndrome as a serious potential sequela of long-term topical pilocarpine use.
ABSTRACT
PURPOSE: To study color vision in patients with oculocutaneous albinism (OCA) METHODS: We evaluated color vision in 42 patients with OCA using the HRR color plates. Sixty seven percent of the patients had the Hermansky-Pudlak syndrome (HPS), diagnosed genetically or clinically. The remaining patients had unknown mutations leading to OCA. RESULTS: 47.6 % of patients of OCA of all types included had a color vision defect. Of these, 55% were female and 45% were male patients. 50% of patients with the HPS (all types) had a color vision deficit. 42.9% of patients with OCA of unknown type had color weakness. 57.1% had normal color vision. CONCLUSIONS: Results suggest that many patients with OCA and the HPS have a mild red-green color perception deficiency that is not a sex linked trait. The prevalence of color vision deficits in our study population increased with decreasing visual acuity.
Subject(s)
Color Perception , Color Vision Defects/etiology , Hermanski-Pudlak Syndrome/complications , Adolescent , Adult , Albinism, Oculocutaneous/classification , Albinism, Oculocutaneous/complications , Albinism, Oculocutaneous/physiopathology , Carrier Proteins/genetics , Child , Child, Preschool , Color Perception/genetics , Color Vision Defects/epidemiology , Color Vision Defects/genetics , Female , Genetic Heterogeneity , Genotype , Hermanski-Pudlak Syndrome/classification , Hermanski-Pudlak Syndrome/genetics , Hermanski-Pudlak Syndrome/physiopathology , Humans , Incidence , Intracellular Signaling Peptides and Proteins , Male , Membrane Proteins/genetics , Middle Aged , Phenotype , Prospective Studies , Visual AcuityABSTRACT
The following presentation deals with a case report of a large true splenic cyst. After a thorough research of the available medical lieature this appears to be the largest reported specimen or this entity
Subject(s)
Adult , Humans , Female , Cysts/surgery , Splenic Diseases/surgery , Cysts , Cysts/pathology , Splenic Diseases , Splenic Diseases/pathology , Tomography, X-Ray ComputedABSTRACT
Se estudió un grupo de pacientes a los cuales se les practicó una colecistectomía debido a colelitiasis asociada a una colecistitis crónica para determinar si había alguna alteación en la flora de la bílis o de la función e histopatología hepática
Subject(s)
Adolescent , Adult , Middle Aged , Humans , Male , Female , Cholecystitis/complications , Chronic Disease , Liver/physiopathology , Biopsy , Cholecystostomy , Clinical Trials as Topic , Cholelithiasis/etiologyABSTRACT
El hipoparatiroidismo permanente luego de una tiroidectomia es una seria complicación quirúrgica que ocurre con una frecuencia aproximada de 1%. La sintomatología usualmente se manifiesta en el período post-operatorio immediato y requiere de un tratamiento rápido y adecuado. Presentamos el caso de un paciente con el hallazgo poco usual de un estado hipoparatiroideo severo con un valor de calcio sérico muy por debajo de lo normal y sin manifestaciones clínicas luego de cirugía de la tiroide. Se discuten también los factores responsables por esta condición, y se enfatiza algunos aspectos técnicos para la protección del tejido paratiroideo y de su vascularidade durante cirugía
