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Pharmazie ; 40(4): 248-9, 1985 Apr.
Article in German | MEDLINE | ID: mdl-4011656

ABSTRACT

The applicability of liquid membrane electrodes for estimation of partition coefficients is demonstrated. The correlation of selectivity coefficients of electrodes based on tricaprylmethylammonium-ion pairs with the octanol/water partition coefficients is demonstrated for several barbiturates. It is statistically significant and allows a simple estimation of partition coefficients.


Subject(s)
Barbiturates/analysis , Solubility , Chemistry, Pharmaceutical , Electrodes , Membranes, Artificial
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