Subject(s)
Acute Lung Injury/chemically induced , Granulocyte Colony-Stimulating Factor/adverse effects , Hematopoietic Stem Cell Mobilization/adverse effects , Lung Diseases, Interstitial/etiology , Peripheral Blood Stem Cell Transplantation , Unrelated Donors , Acute Kidney Injury/chemically induced , Acute Lung Injury/etiology , Adult , Bronchitis/complications , Enterococcus faecium , Female , Gram-Positive Bacterial Infections/complications , Gram-Positive Bacterial Infections/microbiology , Granulocyte Colony-Stimulating Factor/pharmacology , Humans , Influenza A Virus, H1N1 Subtype/isolation & purification , Influenza B virus/isolation & purification , Influenza, Human/complications , Influenza, Human/virology , Lenograstim , Lung Diseases, Interstitial/drug therapy , Male , Otitis Media/complications , Otitis Media/microbiology , Pleural Effusion/etiology , Pneumonia, Viral/complications , Pneumonia, Viral/virology , Prednisone/therapeutic use , Recombinant Proteins/adverse effects , Recombinant Proteins/pharmacology , Young AdultABSTRACT
The correlation between lung function and the quality of oesophageal speech was investigated in 36 patients who had undergone laryngectomy with glottoplasty. It was found that this correlation did not depend on any important lung function parameters. Lung tests were carried out on 10 patients before and after laryngectomy. No changes in lung function could be found that may have been directly attributed to a laryngectomy. This means that restrictive or obstructive lung disturbances do not contra-indicate glottoplasty or a Blom-Singer-puncture.
Subject(s)
Glottis/surgery , Lung/physiopathology , Voice Quality , Voice , Aged , Female , Humans , Laryngectomy , Larynx, Artificial , Male , Middle Aged , Respiratory Function Tests , Surgery, PlasticABSTRACT
The developmental kinetics of the inner ear of 2- to 30-mm embryos are examined. The development of the inner ear can be shown as being constructively correlated with the development of the brain and thus being an ontogenic requisite for the structural development of the embryo. The development kinetic findings, as shown here, demonstrate that the functions of the inner ear have already started during its development and differentiation.
Subject(s)
Ear, Inner/embryology , Auditory Pathways/embryology , Brain/embryology , Cell Differentiation , Cochlea/embryology , Dendrites/ultrastructure , Ear, Inner/cytology , Ear, Inner/innervation , Endolymphatic Duct/embryology , Female , Gestational Age , Humans , Kinetics , Pregnancy , Saccule and Utricle/embryologySubject(s)
Pancreatic Juice/analysis , Pancreatitis/diagnosis , Ultrasonography , Cholecystokinin , Chronic Disease , Humans , SecretinABSTRACT
A specific and sensitive solid-phase radioimmunoassay has been developed for the detection of LCM virus antigens and anti-LCM virus antibodies. The test was performed in a microtiter system using polyvinylcholoride wells coated with anti-LCM virus rabbit hyperimmune serum. LCM virus antigens were allowed to bind to this antibody and afterwards detected by 125J-labeled anti-LCM virus-gamma-globulin. Anti-LCM virus antibodies were assayed by specific inhibition of these bound antigens. Since this technique is rapid and easy to perform the solid-phase radioimmunoassay is a valuable test for detecting LCM virus infections. Selected at random, 208 girls with, and 208 girls without, contact to Syrian hamsters were investigated for anti-LCM virus antibodies. Five (2.4%) of the hamster-exposed girls had anti-LCM virus antibodies (RIA-titer 1:8-1:32) in contrast to none of the control group (P=0.03).
Subject(s)
Antibodies, Viral/analysis , Antigens, Viral/analysis , Health Surveys , Lymphocytic choriomeningitis virus/immunology , Animals , Antibody Specificity , Binding Sites, Antibody , Cricetinae , Female , Humans , Lymphocytic Choriomeningitis/epidemiology , Mesocricetus , RadioimmunoassayABSTRACT
LCM virus, strain WE--grown on L cells--and labeled with 3H-uridine was centrifuged to equilibrium in a sucrose density gradient and examined in fractions for infectivity, incorporated radioactivity, and electron-microscopic features. The peak of infectivity is congruent with the one of radioactivity (density = 1.17 g/ml). LCM virus specificity of the radioactive peak was proved by precipitation of the radioactivity with anti-LCM virus antiserum. The peak fractions showed an abundance of 106 +/- 14 nm (1s) particles. They could be agglutinated with specific anti-LCM virus antiserum but not with antiserum directed against the histocompatibility (H-2) antigens of L cells.