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Klin Med (Mosk) ; 78(6): 46-8, 2000.
Article in Russian | MEDLINE | ID: mdl-10900871

ABSTRACT

Effects of cosaar (MSD) on central hemodynamics and microcirculation were studied in 20 patients with arterial hypertension under acute pharmacological test and on the treatment week 2, 6 and 8. Two variants of hemodynamic response were registered: hypokinetic and hyperkinetic. Unidirectional hemodynamic changes occurred both in short- and long-term therapy. This allows to use the short course for differential choice of patients for cosaar therapy. The best effect of cosaar is expected in patients with a hyperkinetic variant of the hemodynamic response under the short treatment course.


Subject(s)
Antihypertensive Agents/administration & dosage , Hypertension/drug therapy , Losartan/administration & dosage , Adult , Blood Pressure , Female , Humans , Hypertension/physiopathology , Male , Microcirculation/drug effects , Middle Aged , Myocardial Contraction/drug effects , Treatment Outcome
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