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J Proteome Res ; 18(3): 1426-1432, 2019 03 01.
Article in English | MEDLINE | ID: mdl-30667224

ABSTRACT

The use of mass-spectrometry-based techniques for global protein profiling of biomedical or environmental experiments has become a major focus in research centered on biomarker discovery; however, one of the most important issues recently highlighted in the new era of omics data generation is the ability to perform analyses in a robust and reproducible manner. This has been hypothesized to be one of the issues hindering the ability of clinical proteomics to successfully identify clinical diagnostic and prognostic biomarkers of disease. P-Mart ( https://pmart.labworks.org ) is a new interactive web-based software environment that enables domain scientists to perform quality-control processing, statistics, and exploration of large-complex proteomics data sets without requiring statistical programming. P-Mart is developed in a manner that allows researchers to perform analyses via a series of modules, explore the results using interactive visualization, and finalize the analyses with a collection of output files documenting all stages of the analysis and a report to allow reproduction of the analysis.


Subject(s)
Biomarkers , Mass Spectrometry/statistics & numerical data , Proteomics/statistics & numerical data , Software , Humans , Internet , Ions/chemistry , Mass Spectrometry/methods , Prognosis , Proteomics/methods
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