ABSTRACT
We present the clinical findings, diagnosis and treatment of an 11-year old intact male Fox Terrier with a malignant Leydig cell tumor of the right testicle, which metastasized to the skeletal musculature of the left hind limb. The primary tumor and the metastasis were resected with narrow margins. The dog was treated with metronomic chemotherapy using thalidomid and dyclophosphamide. Local recurrence at the site of the metastasis and a pulmonary metastasis were present 30 months after surgery. The dog was euthanized.
Subject(s)
Dog Diseases/pathology , Leydig Cell Tumor/veterinary , Muscle Neoplasms/veterinary , Neoplasm Recurrence, Local/veterinary , Testicular Neoplasms/veterinary , Administration, Metronomic/veterinary , Angiogenesis Inhibitors/administration & dosage , Animals , Antineoplastic Agents, Alkylating/administration & dosage , Chemotherapy, Adjuvant/veterinary , Cyclophosphamide/administration & dosage , Dog Diseases/diagnosis , Dog Diseases/therapy , Dogs , Euthanasia, Animal , Fatal Outcome , Hindlimb , Leydig Cell Tumor/diagnosis , Leydig Cell Tumor/secondary , Leydig Cell Tumor/therapy , Lung Neoplasms/diagnosis , Lung Neoplasms/secondary , Lung Neoplasms/veterinary , Male , Muscle Neoplasms/diagnosis , Muscle Neoplasms/secondary , Muscle Neoplasms/therapy , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/therapy , Testicular Neoplasms/diagnosis , Testicular Neoplasms/pathology , Testicular Neoplasms/therapy , Thalidomide/administration & dosageABSTRACT
In human medicine positron emission tomography (PET) is a modern diagnostic imaging method. In the present paper we outline the physical principles of PET and give an overview over the main clinic fields where PET is being used, such as neurology, cardiology and oncology. Moreover, we present a current project in veterinary medicine (in collaboration with the Paul Scherrer Institute and the University Hospital Zurich), where a hypoxia tracer is applied to dogs and cats suffering from spontaneous tumors. Finally new developments in the field of PET were discussed.
Subject(s)
Tomography, Emission-Computed/veterinary , Veterinary Medicine/instrumentation , Veterinary Medicine/methods , Animals , Diagnostic Techniques, Neurological/veterinary , Heart Diseases/diagnosis , Heart Diseases/diagnostic imaging , Heart Diseases/veterinary , Humans , Image Processing, Computer-Assisted , Neoplasms/diagnosis , Neoplasms/diagnostic imaging , Neoplasms/veterinary , Tomography, Emission-Computed/instrumentation , Tomography, Emission-Computed/methodsABSTRACT
Palliative radiation therapy may provide significant relief in symptoms in pets with incurable cancer. Therapy is applied over a short period of time, using larger than normal fractional doses. Palliative radiation leads to minimal or no side effects. This case report describes the situation of a miniature poodle that was presented with severe dyschezia as well as fresh blood in the feces. The dog had a large abdominal mass which was diagnosed as lymph-node metastasis of a perianal gland carcinoma. Therapy included palliative radiation as well as chemotherapy. Six months after initial presentation the dog is free of clinical symptoms.
