ABSTRACT
The authors report on a case of disseminated coccidioidomycosis of the medial cuneiform. This is a rare finding, with only a few reports of Coccidioides immitis being cultured from the bones of the foot. A brief overview of coccidioidomycosis, pertinent imaging studies, and histopathologic evaluation are presented.
Subject(s)
Coccidioides/isolation & purification , Coccidioidomycosis/diagnosis , Tarsal Bones/microbiology , Tendinopathy/diagnosis , Adult , Animals , Coccidioidomycosis/therapy , Diagnosis, Differential , Female , HumansABSTRACT
A 37-year-old white man had untreated lymphomatoid papulosis for 12 years before a submandibular T cell immunoblastic lymphoma developed. A genetic abnormality, composed of extra chromosomal material attached to the short arm of chromosome 9, was detected in the lymphoma tissue but not in the skin. The lymphomatoid papulosis skin lesions did not manifest clonal T cell receptor gene rearrangements, but the submandibular lymphoma tissue was clonal and of T cell lineage. The patient's lymphoma responded well to combination chemotherapy, but the lymphomatoid papulosis remains active.
Subject(s)
Lymphoma, Non-Hodgkin/pathology , Skin Diseases/pathology , Adult , Blotting, Southern , Chromosomes, Human, Pair 9 , Gene Rearrangement, beta-Chain T-Cell Antigen Receptor , Humans , Lymphoma, Non-Hodgkin/genetics , Lymphoma, Non-Hodgkin/immunology , Male , Skin Diseases/genetics , Skin Diseases/immunology , T-Lymphocytes/immunology , Translocation, GeneticABSTRACT
Ankle stability in basketball players is affected by footwear. Athletic shoe manufacturers have introduced specialized lacing systems and high-top performance shoes to improve ankle stability. These performance shoes not only aid in preventing ankle injuries, but also protect injured ankles.
Subject(s)
Ankle Injuries , Athletic Injuries/prevention & control , Basketball , Shoes , Sports , Ankle Joint/anatomy & histology , Athletic Injuries/epidemiology , Equipment Design , Female , Humans , Immobilization , Male , Shoes/standards , Sprains and Strains/epidemiology , Sprains and Strains/prevention & controlABSTRACT
A woman aged 60, who had been immunosuppressed since receiving a renal transplant 17 years before, developed a painless ulcerated lesion on her right labia majora. Cryptococcus neoformans was demonstrated by culture and biopsy of the lesion. This is the first reported case of a genital skin lesion caused by C neoformans.
