[Silent myocardial ischemia in long-term ECG with various mani festations of coronary heart disease]. / Stumme Myokardischämie im Langzeit-EKG bei verschiedenen Manifestationsformen der koronaren Herzkrankheit.

Silent myocardial ischaemia seems to be of prognostic value in coronary artery disease. We examined 47 patients with coronary artery disease: 1. 20 patients with a history of myocardial infarction (MI), 2. 15 patients with chronic stable angina pectoris without a history of myocardial infarction (sAP), and 3. twelve patients with unstable angina with or without a history of myocardial infarction (uAP). Horizontal and downsloping ST-segment-depressions greater than or equal to 1 min and greater than or equal to 0.1 mV were defined as significant. There were 132 ST-segment-depressions, the relation between symptomatic and asymptomatic being 1:7.3, in MI 1:6.2, in sAP 1:5.3, in uAP 1:14. Heart rate increased before beginning of ST-segment-depression in 74% in MI, in 86% in sAP, but only in 38% in uAP. In sAP ST-segment-depressions were smaller (14% greater than 0.2 mV, none greater than 0.3 mV) than in patients with MI (42% greater than 0.2 mV, 12% greater than 0.3 mV) and uAP (25% greater than 0.2 mV, 9% greater than 0.3 mV). Mean duration of ST-segment-depression was 15.3 +/- 11.7 min in sAP (2 to 49 min), 28.5 +/- 35.6 min in MI (2 to 168 min), and 41.2 +/- 40 min in iAP (2 to 140 min). ST-segment-depressions in MI and sAP showed a circadian rhythm with a peak at midday and in the early evening and a small amount of ST-segment-depressions at night. In uAP ST-segment-depressions did not show that circadian variation. The number of ST-segment-depressions was higher in uAP than in MI and sAP.(ABSTRACT TRUNCATED AT 250 WORDS)

[Comparison of the suitability of first time and related blood donors]. / Eignungsvergleich von Erst- und Verwandtenspendern.

In order to lessen the fear of transfusion-transmitted AIDS, formalized autologous and directed donation programs have been established. The advantages of directed donations, however, have been questioned. A comparison of the qualification of first time homologous and directed donations showed in our groups significant differences for HBsAg positivity, ESR and hemoglobin. The high rate of HBsAg positivity had to be attributed to directed donors of Turkish nationality due to the different epidemiological situation. It seems that directed donations do not improve transfusion safety.