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2.
Neurol Neurochir Pol ; 44(1): 91-5, 2010.
Article in English | MEDLINE | ID: mdl-20358489

ABSTRACT

Giant "invasive" schwannomas of the spine occur occasionally, most frequently in the lumbar region. We present the case of a 46-year-old woman with giant "invasive" schwannoma of the lumbar spine, with a 12-year history of illness. The tu-mour originated in the vertebral canal and passed through the paraspinal muscles and retroperitoneal area to the abdominal cavity. The part of the tumour which was in the abdominal cavity was removed by means of laparotomy during the first operation. In the second one, the remaining part of the tumour was removed completely from the vertebral canal and retroperitoneal area through posterior-lateral access. The spine was stabilized with metal implants. Histological examination revealed cellular schwannoma. During the follow-up the pain resolved while paresis of the right quadriceps muscle of the thigh was still present. Cellular schwannoma is a benign form of schwannoma, but it may cause a local recurrence if not removed completely.


Subject(s)
Lumbar Vertebrae/pathology , Lumbar Vertebrae/surgery , Neurilemmoma/diagnosis , Neurilemmoma/surgery , Spinal Neoplasms/diagnosis , Spinal Neoplasms/surgery , Female , Humans , Lumbar Vertebrae/diagnostic imaging , Middle Aged , Neurilemmoma/diagnostic imaging , Neurilemmoma/pathology , Radiography , Rare Diseases , Spinal Fusion , Spinal Neoplasms/diagnostic imaging , Spinal Neoplasms/pathology , Treatment Outcome
3.
Neurol Neurochir Pol ; 42(4): 323-31, 2008.
Article in English | MEDLINE | ID: mdl-18975237

ABSTRACT

BACKGROUND AND PURPOSE: Neoplastic disease damages the spine more often than trauma. Metastatic tumour causes vertebral column instability and neurological deficit. Surgical intervention indications depend on the patient's general and neurological status. The aim of neuro-orthopaedic treatment is to achieve pain relief and neurological improvement. Spine stability is secured by various implant systems. The aim of the paper is to present indications, operative techniques and stabilisation methods in patients with metastatic spine disease. MATERIAL AND METHODS: There were 73 patients included in this study: 50 males and 23 females, aged 17-74 years. The dominant tumour location was the thoracic spine (41 cases), followed by the lumbar spine (19). Symptoms of spinal cord lesion were observed in 71 patients. Qualification for surgery and approach planning were based on different scales (ASA, DeWald, Frankel, Karnofsky, Denis, Tomita). Internal stabilisation implantation followed tumour resection. RESULTS: Anterior approach was used in 15 cases, posterolateral in 39, posterior in 13, and combined in 6 cases. Histological findings generally allowed the primary tumour location to be disclosed, which in most cases involved the kidney, prostate, lung and the haematopoietic system. Neurological improvement was observed in 82% of cases. Perioperative death occurred in 3% of all patients. CONCLUSIONS: Employed operative techniques are adequate for tumour removal, neural and vascular structures decompression and for implant placement.


Subject(s)
Fracture Fixation, Internal/methods , Spinal Fusion/methods , Spinal Neoplasms/secondary , Spinal Neoplasms/surgery , Spine/surgery , Adolescent , Adult , Aged , Cervical Vertebrae/surgery , Female , Humans , Intervertebral Disc/surgery , Lumbar Vertebrae/surgery , Male , Middle Aged , Poland , Retrospective Studies , Spine/pathology , Survival Analysis , Thoracic Vertebrae/surgery , Treatment Outcome
4.
Neurol Neurochir Pol ; 42(3): 223-30, 2008.
Article in English | MEDLINE | ID: mdl-18651328

ABSTRACT

BACKGROUND AND PURPOSE: Scar formation after spine surgery in the lumbosacral region may be the cause of failed back surgery syndrome. Therefore efforts are made to find materials preventing excessive scar formation at the site of surgery. The aim of the study was to evaluate the usefulness of TachoComb application in prevention of epidural scar formation in a rat experimental model. This paper additionally presents a review of literature concerning other methods of local suppression of scar formation after posterior approaches to the lumbar spine. MATERIAL AND METHODS: The experimental study was carried out on 14 male Wistar rats. Rats were divided into 2 groups. Laminectomy was performed in the first group (control group: n=5). In the second group of animals (n=9) laminectomy was followed by TachoComb application on the exposed dura. Neurological condition of the studied animals was evaluated based on clinical observation, neurological tests and recording of somatosensory evoked potentials. Post mortem histological examination was the main method of assessment of the experimental material. RESULTS: Presence of scar in the vertebral canal, its extent and severity differed between experimental groups. Electrophysiological results were also different between studied groups. CONCLUSIONS: TachoComb prevents epidural scar formation after lumbar spine surgery. Its positive effect concerning neural transmission at the level of the medulla was proven by electrophysiological tests in which the amplitude of components I and II of SSEP in the TachoComb group were significantly higher than in the control group.


Subject(s)
Aprotinin/administration & dosage , Cicatrix/drug therapy , Epidural Space/drug effects , Epidural Space/pathology , Fibrinogen/administration & dosage , Lumbar Vertebrae/pathology , Lumbar Vertebrae/surgery , Thrombin/administration & dosage , Animals , Cicatrix/etiology , Disease Models, Animal , Drug Combinations , Fibrosis/drug therapy , Laminectomy/adverse effects , Male , Postoperative Complications/prevention & control , Rats , Rats, Wistar , Spinal Diseases/pathology , Spinal Diseases/surgery , Treatment Outcome
5.
Neurol Neurochir Pol ; 40(6): 501-8, 2006.
Article in Polish | MEDLINE | ID: mdl-17199176

ABSTRACT

BACKGROUND AND PURPOSE: Widespread use of antibiotics resulted in considerable reduction of spondylitis, but despite that progress there are some cases where conservative treatment has failed. In these patients surgical intervention should be carefully considered. Early surgery in patients with increasing neurological deficits causes the uncertainty which exists in relation to possible complications. Fewer doubts are associated with surgical treatment of late consequences (spine deformity, instability, etc). The goal of this study was to present indications for surgery, operative techniques of transpedicular stabilization and results of treatment of thoracic and lumbar spondylitis. MATERIAL AND METHODS: Clinical analysis includes 18 patients with spondylitis treated in the Department of Neurosurgery and Neurotraumatology University of Medical Sciences in Poznan between 1997 and 2004. There were 7 males (39%) and 11 females (61%) in the study group, and their mean age was 57+/-10 years (range 49-69). Spondylitis within thoracic segments was found in 15 (83%) cases and 3 (17%) patients had spondylitis within lumbar segments. Indications for early surgical intervention included increasing neurological symptoms, spine instability and failed conservative treatment. All patients underwent transpedicular stabilization following medulla and nerve root decompression. RESULTS: Non-specific inflammation was observed in 14 (78%) cases, and specific inflammation was discovered in 4 (22%) cases (bacteriological and histopathological findings). Very good and satisfactory results were achieved in 16 (89%) patients. Complications occurred in 4 (22%) patients. CONCLUSIONS: Spondylitic spine surgery limits inflammatory reaction, strengthens diagnosis, repairs vertebral column stability and improves neurological condition. Transpedicular stabilization is an effective method of achieving of internal spondylodesis.


Subject(s)
Spondylitis/surgery , Aged , Female , Humans , Male , Middle Aged , Treatment Outcome
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