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1.
Epilepsy Behav ; 125: 108364, 2021 12.
Article in English | MEDLINE | ID: mdl-34731723

ABSTRACT

From August 27-28, 2020 the Epilepsy Foundation hosted the Pipeline Conference, exploring emerging issues related to antiepileptic drug and device development. The conference featured epilepsy therapeutic companies and academic laboratories developing drugs for focal epilepsies, innovations for rare and ultra-rare diseases, and devices both in clinical trials and approved for use. In this paper, we outline the virtual presentations by the authors, including novel data from their development pipeline.


Subject(s)
Epilepsies, Partial , Epilepsy , Pharmaceutical Preparations , Anticonvulsants/therapeutic use , Epilepsies, Partial/drug therapy , Epilepsy/drug therapy , Humans
2.
Epilepsy Behav ; 111: 107189, 2020 10.
Article in English | MEDLINE | ID: mdl-32563052

ABSTRACT

On May 22-24, 2019, the 15th Antiepileptic Drug and Device (AEDD) Trials Conference was held, which focused on current issues related to AEDD development from preclinical models to clinical prognostication. The conference featured regulatory agencies, academic laboratories, and healthcare companies involved in emerging epilepsy therapies and research. The program included discussions around funding and support for investigations in epilepsy and neurologic research, clinical trial design and integrated outcome measures for people with epilepsy, and drug development and upcoming disease-modifying therapies. Finally, the conference included updates from the preclinical, clinical, and device pipeline. Summaries of the talks are provided in this paper, with the various pipeline therapeutics in the listed tables to be outlined in a subsequent publication.


Subject(s)
Anticonvulsants/therapeutic use , Clinical Trials as Topic , Congresses as Topic/trends , Drug Development/trends , Epilepsy/drug therapy , Animals , Clinical Trials as Topic/methods , Device Approval , Drug Development/methods , Epilepsy/diagnosis , Epilepsy/genetics , Florida , Genetic Testing/methods , Genetic Testing/trends , Humans , Mass Screening/methods , Mass Screening/trends , National Institute of Neurological Disorders and Stroke (U.S.)/trends , United States
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