Subject(s)
Facial Neoplasms/immunology , Jaw Neoplasms/immunology , Mouth Neoplasms/immunology , Antibody Formation , B-Lymphocytes , Facial Neoplasms/surgery , Humans , Immunity, Cellular , Immunoglobulins/analysis , Jaw Neoplasms/surgery , Middle Aged , Mouth Neoplasms/surgery , Neoplasm Staging , T-Lymphocytes/immunologyABSTRACT
In 48 men occupationally exposed to CS2 the following glycoproteins were estimated in blood serum, using radial immunodiffusion on M-Partigen plates: alpha1-acid glycoprotein, alpha1-antitrypsin, alpha2-HS-glycoprotein, alpha2-macroglobulin, Gc glycoprotein, hemopexin, haptoglobin, ceruluplasmin and beta2-glycoprotein I. The studies indicated a highly statistically significant increase of: alpha1-acid--glycoprotein and Gc glycoprotein, and decrease of: alpha1-antitrypsins, alpha2-HS--glycoprotein and beta2-glycoprotein. The level of the remaining glycoproteins was normal.
Subject(s)
Air Pollutants, Occupational/adverse effects , Air Pollutants/adverse effects , Carbon Disulfide/adverse effects , Glycoproteins/blood , Textile Industry , Adult , Ceruloplasmin/analysis , Haptoglobins/blood , Hemopexin/blood , Humans , Male , Middle Aged , Time Factors , alpha 1-Antitrypsin/analysis , alpha-Macroglobulins/analysisSubject(s)
Coronary Disease/blood , Lipids/blood , Myocardial Infarction/blood , Adult , Age Factors , Humans , Male , Middle AgedABSTRACT
beta-Lipoprotein was isolated by the precipitation method from collective serum of 47 men aged 27-49 years (mean 42-1 years) exposed to carbon disulfide during work over long periods of time. Significantly elevated levels of serum beta-lipoprotein, clinical and polycardiographic symptoms were found in 85-1% of subjects. Antibodies to beta-lipoprotein obtained by immunizing rabbits intravenously were compared with similar antibodies in healthy subjects by double immunodiffusion in agar and by the passive hemagglutination test. Both tests showed identical antigens.