Analysis of the fluid contents of simple bone cyst in the mandible.

Description of simple bone cyst (SBC) content has been controversial. This study aimed to assess and give a clearer picture of the SBC cavity contents. Between 2014 and 2016, 19 patients with SBC verified by histopathological examination were included in this study. SBC cavity content was investigated using clinical, radiographic, surgical, and laboratory findings. The difference in components among cavity fluid, blood, and serum was evaluated using a paired sample t-test for statistical analysis. All 19 SBC cases radiographically and surgically revealed a fluid-filled cavity. The patients' average age was 21.3 ± 13.2 years, with no sex predominance found. SBCs were found mostly in the anterior mandible (n = 12, 63.2%). All lesions were filled with clear straw-colored or blood-colored floods with low concentration. Although the fluid components were similar to those in the blood and serum in the laboratory analysis, the statistical analysis revealed that the fluid components were not significantly different only for eosinophil (p = 0.43) and basophil (p = 0.06) counts as blood components and sodium (p = 0.76), potassium (p = 0.08), and chloride (p = 0.13) concentration as serum components. The results show that SBC is a fluid-filled cavity, with the cavity fluid being more likely similar to serum rather than blood regarding internal components.

Analysis of Factors Associated with the Postoperative Healing of Medication-Related Osteonecrosis of the Jaw in Patients with Osteoporosis.

BACKGROUND: Surgical treatment is considered the best approach by many researchers for medication-related osteonecrosis of the jaws (MRONJ). While postoperative outcomes are mainly favorable, wound healing still fails in some cases. This retrospective study aimed to evaluate the factors affecting the postoperative healing of MRONJ. METHODS: This study involved 400 osteoporosis patients who received surgical treatment from January 2009 to January 2018 in Kyungpook National University Hospital. The patient, drug, and clinical factors were collected as investigation variables. The obtained data were statistically analyzed to identify relationships between the factors and healing aspect. RESULTS: Univariate logistic regression analysis showed that the route of drug administration, bone exposure, types of surgical management, and wound management had a significant influence (p < 0.05) on the healing outcome. Sequestrectomy with primary closure had a more positive effect on favorable healing. In the multivariate logistic regression test, the effect of wound management alone was not statistically significant (p > 0.05). CONCLUSION: In patients with osteoporosis, the factors such as intravenously administered drugs, fistulas that were probed to the bone, and surgical management with curettage were associated with a lower rate of postoperative complete healing of MRONJ, whereas primary closure of wounds led, possibly, to good healing outcomes. The strengths of the study include its relatively large sample size and that its results can hopefully aid in the clinical decisions for practitioners and future research studies for researchers.

Comparing factors affecting dental-implant loss between age groups: A retrospective cohort study.

BACKGROUND: There is a growing interest in factors leading to implant failure in older people as the population aged 65 years or older continues to expand. PURPOSE: We sought to identify differences of results in the implant survival rate and the influence of certain factors on implant failure in the older (≥65 years) and younger (<65 years) patients. MATERIALS AND METHODS: Patients who underwent their first dental-implant surgery between July 2008 and June 2018 were included. Data on age, sex, smoking habits, medical conditions, implant location, implant size, and the presence and type of bone graft and membrane were collected and analyzed according to age group. Moreover, cumulative survival rates of implants (by Kaplan-Meier analysis) and hazard ratios (HR) of each factor (using Cox regression analysis with shared frailty) in each group were assessed and results compared between groups. RESULTS: A total of 628 implants in 308 patients and 1904 implants in 987 patients in the older and younger groups, respectively, were assessed, with failure rates of 3.9% and 3.4%. Per Kaplan-Meier analysis, the 11-year patient-level cumulative survival rate of implant treatment was 95.3% (95% CI: 0.91-0.97) in the older and 93.9% (95% CI: 0.88-0.97) in the younger group. The HR for implant failure of the variables, except diameter of dental implants, were not statistically significant in both groups. CONCLUSION: The outcomes of implant treatment were not considerably different between the age groups.