ABSTRACT
Presents literature data and the author's own findings on endocrine system disorders influencing the development and course of opisthorchiasis. The author claims that these shifts are related to disorders of the compensatory adaptive mechanisms occurring in opisthorchiasis.
Subject(s)
Hormones/metabolism , Opisthorchiasis/metabolism , Animals , Endocrine Glands/metabolism , Female , Humans , Male , Opisthorchiasis/parasitology , Opisthorchis/metabolismABSTRACT
Radioimmunoassay was employed to measure blood levels of LH, FSH, testosterone, estradiol, progesterone, estriol, gastrin and cAMP in 184 duodenal ulcer patients (141 males and 43 females) and 81 controls (40 males and 41 females). For duodenal ulcer patients hypophyseal gonadotropic function was activated while the blood picture of sex hormones is sex-related. Functional balance between the study hormones typical for healthy subjects in duodenal ulcer was found impaired. Derangement of hormonal homeostasis of hypophyseal-gonadal system of the blood and its functional relations with gastroduodenal system may be a contributing factor in pathogenesis of peptic ulcer.
