[Effect on the lipid profile of diet supplemented with fish oil concentrate]. / Effekt på lipidprofil av kosttilskudd med fiskeoljekonsentrat.

Effects on serum lipids were examined in a double blind placebo controlled trial including 111 male and females with cholesterol values higher than 7.0 mmol/l. The patients were treated with 6 g Almarin capsules consisting of the highly concentrated fish-oil EPAX 6000 EE in a daily dose corresponding to 2.1 g eicosapentaenoic acid and 1.5 g docosahexaenoic acid, or olive oil control for 12 weeks. We registered the effects on serum triglycerides, total cholesterol and HDL cholesterol. Compared with baseline values a 19.5% median reduction in serum triglycerides could be observed in the n-3 treated group. This reduction was significantly different from control and baseline values. We also observed a favourable trend towards lower total serum cholesterol and higher serum HDL cholesterol.