ABSTRACT
Aim: High expression of lytic enzymes and cytokines is related to cell proliferation in Otitis Media Chronic Suppurative (CSOM) with cholesteatoma. In addition, the process of inflammation healing and maintenance of homeostatic conditions requires Reactive Oxygen Species (ROS), which can cause significant damage to cells. To address this issue, secondary antioxidants such as Vitamins A and E are used to inhibit and neutralize the occurrence of oxidation reactions. These vitamins complement each other, with vitamin A working effectively at low concentrations of oxygen, while vitamin E functions in the opposite manner. Purpose: This study aims to investigate the roles of vitamin A and E levels in CSOM patients with Cholesteatoma. Patients and Methods: The study was conducted between July and December 2020, and the method used was an analytical observational approach with a case-control design. The sample population comprised 60 CSOM patients divided into 2 groups. These included those with and without cholesteatoma. Results: The results showed that there was no significant difference between these two groups in terms of the impact of vitamin A and E levels (respectively, p = 0.626, p = 0.864). Conclusion: Considering these results, it was discovered that vitamins A and E levels do not influence the occurrence of CSOM with or without cholesteatoma.
ABSTRACT
Abstract: Auricle is one of the features that determine the face appearance. Furthermore, its shape and size are influenced by age, gender, and ethnicity. Knowledge of the normal dimensional shape, ear growth patterns, and deformity is important in diagnosing various congeital disorders. The auricle dimensions data in the Deutro-Malay population are still unavailable, specifically for the Sundanese ethnic group. Purpose: To determine the anthropometry of adult auricles in the Sundanese population. Patients and Methods: This was a quantitative descriptive study with a cross-sectional approach. The subjects used were Sundanese aged 18-65 years old who visited the Otorhinolaryngology-Head and Neck Surgery outward at Dr. Hasan Sadikin Hospital, Bandung. Their data were obtained by photogrammetric techniques from the results of the ear photographs captured, which were then measured with ImageJ 1.48 software, and analyzed using descriptive statistics. Results: The mean value of seven anthropometric parameters of Sundanese auricle were as follows: For men, auricle length = 6.29 cm ± 0.47, auricle width = 2.95 cm ± 0.26, auricle floor = 4.71 cm ± 0.49, lobule length = 1.90 cm ± 0.24, lobule width = 1.83 cm ± 0.22, concha length = 2.74 cm ± 0.17, and concha width = 1.43 cm ± 0.15. Meanwhile in women, auricle length = 6.09 cm ± 0.42, auricle width = 2.88 cm ± 0.25, auricle floor = 4.58 cm ± 0.47, lobule length = 1.95 cm ± 0.27, lobule width = 1.82 cm ± 0.21, concha length = 2.57 cm ± 0.21, and concha width = 0.42 cm ± 0.19. Conclusion: In Sundanese ethnic, auricle length, width, and floor, as well as concha length of men tended to be greater than women. However, the women's lobule length was longer compared to men's, while the lobule and concha width tended to be the same.
ABSTRACT
INTRODUCTION: Honey has been reported to accelerate wound healing. The use of honey in wound care mostly uses medicated (Manuka) honey. There are still few who report using Nusantara honey, local honey from Indonesia, as a wound dressing. We report wound care using Nusantara honey in patients with a remarkably open wound due to a ruptured submandibular abscess extending to the submental and right neck. PRESENTATION OF CASE: A 67 years old male patient came with a ruptured submandibular abscess that extends to the submental and right neck. On the right submandibular region, an ulcer extends to submental with a size of 10 × 4 × 3 cm, hyperemic, edema around the wound, fluctuating, with pus and tenderness. The isolated bacteria were Staphylococcus aureus. The patient received combination antibiotic therapy, blood sugar management, necrotomy debridement, tooth extraction, and wound care using Nusantara honey on the sixth day after surgery. An improvement was seen on the 10th day after necrotomy. DISCUSSION: The use of honey for wound care is based on thousands of years of history. Honey can accelerate wound healing and show different effects depending on the phase of wound healing. In addition, honey also has antibacterial properties. CONCLUSION: Applying Nusantara honey to treat raw surfaces can help speed up wound healing and provide cost-efficiency. There were no allergic reactions or secondary bacterial infections after using honey in this patient.
