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1.
Med. clín. soc ; 4(1)abr. 2020.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1386185

ABSTRACT

RESUMEN Introducción: El suicidio asistido y la eutanasia son prácticas realizadas para acortar la vida de los pacientes que sufren de manera insoportable. Objetivo: Valorar la actitud del personal de blanco y estudiantes de un hospital universitario acerca del suicidio asistido y la eutanasia, asimismo demostrar el grado de conocimiento de estos, establecer su postura, identificar las razones por las cuales algunos están en desacuerdo con su legalización y contrastar sus actitudes acerca de la realización de eutanasia o suicidio asistido a pacientes terminales y la realización de dichas prácticas sobre su persona en caso de padecer enfermedades terminales. Metodología: Estudio observacional, descriptivo de corte transversal con muestreo no probabilístico por conveniencia llevado a cabo de febrero a marzo del 2020. La muestra fue 300. Se utilizó un cuestionario de autocumplimiento, distribuido digitalmente a los participantes. Resultados: El 10% ha recibido peticiones de pacientes para acelerar la muerte, el 42,7% ha considerado la idea de acelerar la muerte para terminar con el sufrimiento. El 63,3% aceleraría su muerte en caso de padecer enfermedad terminal. El 32% y 38% está totalmente de acuerdo en legalizar el suicidio asistido y la eutanasia, respectivamente, en caso de enfermedades terminales. El 12,7% lo está en caso de Alzheimer o esclerosis lateral amiotrófica. El 16,7% está a favor de la legalización de la eutanasia en casos de tetraplejía. El motivo de desacuerdo más común (32%) para su legalización fueron las razones persona-les. El 20% y 15,3% cometerían eutanasia y suicidio asistido, respectivamente, en caso de padecer enfermedades terminales. El 34% probablemente cometería eutanasia a un paciente en caso de ser legal. Discusión: La respuesta profesional, científica y humana a las múltiples necesidades durante la fase final está en la medicina paliativa, que es la respuesta frente al derecho de todo ser humano al alivio del sufrimiento.


ABSTRACT Introduction: Assisted suicide and euthanasia are practices carried out to shorten the lives of patients who suffer unbearably. Objectives: Assess the attitude of white staff and students of a university hospital about assisted suicide and euthanasia, also to demonstrate the degree of knowledge of these, establish their position, identify the reasons why some disagree with their legalization and contrast their attitudes about performing euthanasia or assisted suicide to terminally ill patients and the performance of such practices on their person in case of terminal illnesses. Methodology: An observational, descriptive crosssectional study with nonprobability sampling for convenience was carried out from February to March 2020. The sample was 300. A selfcompliance questionnaire was used, distributed digitally to the participants. Results: 10% have received requests from patients to accelerate death, 42.7% have considered the idea of accelerating death to end suffering. 63.3% would accelerate their death in case of terminal illness. 32% and 38% fully agree to legalize assisted suicide and euthanasia, respectively, in case of terminal illness. 12.7% is in case of Alzheimer or amyotrophic lateral sclerosis. 16.7% fully agree with the legalization of euthanasia in cases of tetraplegia. The most common reason for disagreement (32%) for its legalization was personal reasons. 20% and 15.3% would commit euthanasia and assisted suicide, respectively, if they suffer from terminal illnesses. 34% would probably euthanize a patient if it were legal. Discussion: The professional, scientific and human response to the multiple needs during the final phase is in palliative medicine, which is the response to the right of every human being to alleviate suffering.

2.
Curr Top Med Chem ; 19(22): 1962-1980, 2019.
Article in English | MEDLINE | ID: mdl-31345151

ABSTRACT

Among the ophidians that inhabit the Northeast of Argentina, the genus Bothrops such as B. alternatus and B. diporus species (also known as yararás) and Crotalus durisus terrificus (named cascabel), represent the most studied snake venom for more than thirty years. These two genera of venomous snakes account for the majority of poisonous snake envenomations and therefore, constitute a medical emergency in this region. This review presents a broad description of the compiled knowledge about venomous snakebite: its pathophysiological action, protein composition, isolated toxins, toxin synergism, toxin-antitoxin cross-reaction assays. Properties of some isolated toxins support a potential pharmacological application.


Subject(s)
Snake Venoms/pharmacology , Toxins, Biological/pharmacology , Animals , Argentina , Bothrops , Crotalus , Humans , Snake Venoms/chemistry , Snake Venoms/isolation & purification , Toxins, Biological/chemistry , Toxins, Biological/isolation & purification
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