ABSTRACT
The authors describe a 9 year-old girl with homozygous deficiency of C2 component, causing null activity of the classical pathway of complement. The girl suffered from several recurrent infections since birth, later developed signs of the Henoch-Schönlein disease. At the age of 1 1/2 years she was hospitalized due-to bacterial meningitis, most probably of Neisseria meningitis etiology.
Subject(s)
Complement C2/deficiency , Immune System Diseases/congenital , Child , Female , Humans , Immune System Diseases/diagnosis , Infections/etiology , Meningitis, Bacterial/etiology , RecurrenceABSTRACT
In this review the data on glycosyl-phosphatidylinositol anchored protein deficiency occurring on different cells in paroxysmal nocturnal haemoglobinuria are presented. In addition different diagnostic methods in PNH are discussed.
Subject(s)
Blood Cells/metabolism , Glycosylphosphatidylinositols/deficiency , Hemoglobinuria, Paroxysmal/blood , Hemoglobinuria, Paroxysmal/diagnosis , Humans , Membrane Proteins/metabolismABSTRACT
Results of serological tests for syphilis performed on donors and patients at the Institute of Haematology over the last two years are summarized. The results of tests performed by cardiolipins ++ USR and VDRL antigens, and later confirmed using FTA-ABS and TPHA methods were evaluated. They indicate that the recently produced USR antigen is more sensitive and more specific than VDRL antigen. Similarly, TPHA proves to be more sensitive than FTA-ABS test in these prophylactic assays.
