[Iron deficiency anemia in elderly and senile patients.]

Anemic syndrome is common in 1/3 of the population, including iron deficiency anemia - in 1,5 billion people. Geriatric patients are one of the main risk group for anemia. Iron deficiency and iron deficiency anemia lead to a decrease in quality of life, an increase in morbidity and mortality, what requires timely diagnosis and treatment. The diagnostic algorithm includes the analysis of iron metabolism, inflammation markers and instrumental tests to verify the cause of anemia. Modern oral and parenteral iron preparations are used for treatment under control of blood indexes and iron metabolism parameters.

Chiral Surface Twists and Skyrmion Stability in Nanolayers of Cubic Helimagnets.

Theoretical analysis and Lorentz transmission electron microscopy (LTEM) investigations in an FeGe wedge demonstrate that chiral twists arising near the surfaces of noncentrosymmetric ferromagnets [Meynell et al., Phys. Rev. B 90, 014406 (2014)] provide a stabilization mechanism for magnetic Skyrmion lattices and helicoids in cubic helimagnet nanolayers. The magnetic phase diagram obtained for freestanding cubic helimagnet nanolayers shows that magnetization processes differ fundamentally from those in bulk cubic helimagnets and are characterized by the first-order transitions between modulated phases. LTEM investigations exhibit a series of hysteretic transformation processes among the modulated phases, which results in the formation of the multidomain patterns.

Three-dimensional chiral skyrmions with attractive interparticle interactions.

We introduce a new class of isolated three-dimensional skyrmion that can occur within the cone phase of chiral magnetic materials. These novel solitonic states consist of an axisymmetric core separated from the host phase by an asymmetric shell. These skyrmions attract one another. We derive regular solutions for isolated skyrmions arising in the cone phase of cubic helimagnets and investigate their bound states.

[ANEMIC SYNDROME AND ITS SPECIFICS IN SENIOR PATIENTS].

Clinical practice confirms high frequency of anemic syndrome. Anemia is diagnosed more often in senior patients than on the average. The most prevalent type of anemia in senior groups are iron deficiency anemia and B12-deficiency anemia, anemia of chronic diseases and anemia caused by kidney diseases. The cause of anemic syndrome in 25% of senior patients remains unclear. Anemia leads to impairment of life quality, increased morbidity and mortality in senior people except for patients with anemia of unknown origin.

Theory of skyrmion states in liquid crystals.

Within the Oseen-Frank theory we derive numerically exact solutions for axisymmetric localized states in chiral liquid crystal layers with homeotropic anchoring. These solutions describe recently observed two-dimensional skyrmions in confinement-frustrated chiral nematics [P. J. Ackerman et al., Phys. Rev. E 90, 012505 (2014)]. We stress that these solitonic states arise due to a fundamental stabilization mechanism responsible for the formation of skyrmions in cubic helimagnets and other noncentrosymmetric condensed-matter systems.

[Heavy metals as a factor of possible environmentally caused illnesses in the Astrakhan region].

There are presented data about heavy metals as pollutants of the environment and the factors of environment-related diseases. There is given the brief information about the appearance of heavy metals in the environmental objects and the possible occurrence of diseases caused by trace elements deficiency in the region. There are discussed difficulties of the clinical and laboratory diagnosis, associated with general symptoms of many diseases and lack in the medical facilities the equipment for objective detection of heavy metals in human biosubstrates.

Confinement of chiral magnetic modulations in the precursor region of FeGe.

We report on magnetic susceptibility and specific heat measurements of the cubic helimagnet FeGe in external magnetic fields and temperatures near the onset of long-range magnetic order at TC = 278.2(3) K. Pronounced anomalies in the field-dependent χac(H) data as well as in the corresponding imaginary part χ''ac(H) reveal a precursor region around TC in the magnetic phase diagram. The occurrence of a maximum at T0 = 279.6 K in the zero-field specific heat data indicates a second-order transition into a magnetically ordered state. A shoulder evolves above this maximum as a magnetic field is applied. The field dependence of both features coincides with crossover lines from the field-polarized to the paramagnetic state deduced from χac(T) at constant magnetic fields. The experimental findings are analyzed within the standard Dzyaloshinskii theory for cubic helimagnets. The remarkable multiplicity of modulated precursor states and the complexity of the magnetic phase diagram near the magnetic ordering are explained by the change of the character of solitonic inter-core interactions and the onset of specific confined chiral modulations in this area.

[Peculiarities of treatment of elderly and old patients with femoral neck fractures].

The article presents a review of recent issues of diagnostics and general and surgical treatment of the aged patients with cervical hip fractures. The authors describe an approach of surgical treatment of these fractures requiring enhanced "vital" indications for operation in case of the aged patients due to their desperate state. In compliance with a patient's general state, level of physical activity, bone tissue state the authors formulate indications for inner osteosynthesis, unipolar, bipolar or total endoprosthesis replacement.

Precursor phenomena at the magnetic ordering of the cubic helimagnet FeGe.

We report on detailed magnetic measurements on the cubic helimagnet FeGe in external magnetic fields and temperatures near the onset of long-range magnetic order at T(C)=278.2(3) K. Precursor phenomena display a complex succession of temperature-driven crossovers and phase transitions in the vicinity of T(C). The A-phase region, present below T(C) and fields H<0.5 kOe, is split in several pockets. The complexity of the magnetic phase diagram is theoretically explained by the confinement of solitonic kinklike or Skyrmionic units that develop an attractive and oscillatory intersoliton coupling owing to the longitudinal inhomogeneity of the magnetization.

Quantum order in the chiral magnet MnSi.

Systems lacking inversion symmetry, such as selected three-dimensional compounds, multilayers and surfaces support Dzyaloshinsky-Moriya (DM) spin-orbit interactions. In recent years DM interactions have attracted great interest, because they may stabilize magnetic structures with a unique chirality and non-trivial topology. The inherent coupling between the various properties provided by DM interactions is potentially relevant for a variety of applications including, for instance, multiferroic and spintronic devices. The, perhaps, most extensively studied material in which DM interactions are important is the cubic B20 compound MnSi. We review the magnetic field and pressure dependence of the magnetic properties of MnSi. At ambient pressure this material displays helical order. Under hydrostatic pressure a non-Fermi liquid state emerges, where a partial magnetic order, reminiscent of liquid crystals, is observed in a small pocket. Recent experiments strongly suggest that the non-Fermi liquid state is not due to quantum criticality. Instead it may be the signature of spin textures and spin excitations with a non-trivial topology.

[S. P. Botkin--the founder of the domestic clinical gerontology].

The first in the world large-scale gerontology investigation where 2620 elderly patients were examined was carried out by guidance professor S. P. Botkin in St.-Petersburg. The results were published in 1890 in the special book and consisted of 93 papers, including 102 tables.

Spontaneous skyrmion ground states in magnetic metals.

Since the 1950s, Heisenberg and others have addressed the problem of how to explain the appearance of countable particles in continuous fields. Stable localized field configurations were searched for an ingredient for a general field theory of elementary particles, but the majority of nonlinear field models were unable to predict them. As an exception, Skyrme succeeded in describing nuclear particles as localized states, so-called 'skyrmions'. Skyrmions are a characteristic of nonlinear continuum models ranging from microscopic to cosmological scales. Skyrmionic states have been found under non-equilibrium conditions, or when stabilized by external fields or the proliferation of topological defects. Examples are Turing patterns in classical liquids, spin textures in quantum Hall magnets, or the blue phases in liquid crystals. However, it has generally been assumed that skyrmions cannot form spontaneous ground states, such as ferromagnetic or antiferromagnetic order, in magnetic materials. Here, we show theoretically that this assumption is wrong and that skyrmion textures may form spontaneously in condensed-matter systems with chiral interactions without the assistance of external fields or the proliferation of defects. We show this within a phenomenological continuum model based on a few material-specific parameters that can be determined experimentally. Our model has a condition not considered before: we allow for softened amplitude variations of the magnetization, characteristic of, for instance, metallic magnets. Our model implies that spontaneous skyrmion lattice ground states may exist generally in a large number of materials, notably at surfaces and in thin films, as well as in bulk compounds, where a lack of space inversion symmetry leads to chiral interactions.

Skyrmions in nematic liquid crystals.

Analytical solutions for static two-dimensional axisymmetric localized states minimizing the Frank free energy for nematic liquid crystals have been derived. These solitonic structures (skyrmions) include the well-known Belavin-Polyakov solutions as a special case for equal elastic constants. The structure and the equilibrium parameters of these nematic skyrmions crucially depend on values of the elastic constants. Stability limits of these structures and the possibility to observe them in nematic liquid crystals are discussed.

[Electro-impulse therapy in combined treatment of patients with thyrotoxic goiter complicated by cardiac fibrillation]. / Elektroimpul'snaia terapiia v kompleksnom lechenii bol'nykh s tireotoksicheskim zobom, oslozhnennym mertsiatel'noi aritmiei.

Cardiac fibrillation was revealed at admission in 260 (5.2%) of 4996 patients who were to undergo subtotal resection of thyroid gland for toxic goiter. In 114 (43.8%) patients sinus rhythm was restored with drugs in preoperative period. Electroimpulse therapy was carried out in other 146 patients which was effective in 89% cases. Efficacy of electroimpulse therapy depended mainly on the arrhythmia duration. Restoration of sinus rhythm before operation in patients with toxic goiter improves conditions of preoperative preparation and decreases the risk of surgical treatment. There were no lethal outcomes.

Chiral symmetry breaking in magnetic thin films and multilayers.

A phenomenological theory of chiral symmetry breaking in magnetic nanostructures is developed considering induced, inhomogeneous chiral interactions (Dzyaloshinsky-Moriya-type). Application of the theory to films and multilayers with in-plane and out-of-plane magnetization predicts modulated and two-dimensional localized patterns (vortices). These new classes of magnetic patterns are intrinsically stable and localized on nanometer scale. Various experimental observations agree qualitatively with structures derived from this theory.