ABSTRACT
The 1953 drawing by Netter of the thalamus mistakenly placed the dorsolateral nucleus on the wrong side of the internal medullary lamina. This error has been perpetuated in the best known texts on neuroscience for over fifty years.
Subject(s)
Medical Illustration/history , Neuroanatomy/history , Thalamic Nuclei/anatomy & histology , Functional Laterality , History, 20th Century , Humans , Models, Anatomic , Thalamic Nuclei/physiology , Thalamus/anatomy & histology , Thalamus/physiologyABSTRACT
A neurophysiological hypothesis is offered, together with supporting literature, that hemineglect and/or extinction from a temporo-paneto-occipital lesion (and possibly other lesions) can be understood as the unavailability to consciousness of information well represented in brain, the unavailability being the consequence of temporarily suppressing tonic inhibition of corticothalamic interaction no longer balanced by facilitation from the damaged cortex.
Subject(s)
Brain Injuries/physiopathology , Cerebral Cortex/physiopathology , Inhibition, Psychological , Perceptual Disorders/physiopathology , Animals , Arousal/physiology , Consciousness , Functional Laterality/physiology , Humans , Thalamus/physiopathologyABSTRACT
This study quantitatively explored the dendritic/spine extent of supragranular pyramidal neurons across several cortical areas in two adult male subjects who had undergone a callosotomy several decades before death. In all cortical areas, there were numerous atypical, supragranular pyramidal neurons with elongated "tap root" basilar dendrites. These atypical cells could be associated with an underlying epileptic condition and/or could represent a compensatory mechanism in response to deafferentation after callosotomy.
