ABSTRACT
Durante las últimas décadas la infección por virus del papiloma humano (VPH) ha emergido como una nueva epidemia y se ha convertido en un problema de salud debido a su asociación con diversos cánceres localizados en el cuello uterino, región anogenital y orofaringe. En esta revisión pretendemos entender y explicar las características distintivas de los carcinomas escamosos de orofaringe) relacionados con el VPH, en términos de epidemiología, factores de riesgo, topografía específica, subtipos de VPH más frecuentemente involucrados, técnicas de detección del VPH, comportamiento clínico, pronóstico, tratamiento y prevención. También se discutirá la relación del VPH con el desarrollo de otros cánceres de cabeza y cuello y con la patología benigna de la cavidad oral
Over the last few decades, the human papillomavirus (HPV) infection has emerged as a new epidemic and become a health issue due to its involvement in several cancers affecting the cervix, the anogenital region and the oropharynx. In this review, we aim to understand and explain the distinctive features of HPV-related oropharyngeal squamous cell carcinoma based on its epidemiological data, risk factors, specific topography, HPV subtypes most frequently involved, HPV-status diagnosis, clinical behaviour, prognosis, treatment, and preventive measures. In addition, the relationship of HPV with the development of other head and neck carcinomas and benign lesions of the oral cavity will also be discussed
Subject(s)
Humans , Female , Middle Aged , Papillomavirus Infections/complications , Human papillomavirus 16/pathogenicity , Human papillomavirus 6/pathogenicity , Mouth/pathology , Risk Factors , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/pathologyABSTRACT
Over the last few decades, the human papillomavirus (HPV) infection has emerged as a new epidemic and become a health issue due to its involvement in several cancers affecting the cervix, the anogenital region and the oropharynx. In this review, we aim to understand and explain the distinctive features of HPV-related oropharyngeal squamous cell carcinoma based on its epidemiological data, risk factors, specific topography, HPV subtypes most frequently involved, HPV-status diagnosis, clinical behaviour, prognosis, treatment, and preventive measures. In addition, the relationship of HPV with the development of other head and neck carcinomas and benign lesions of the oral cavity will also be discussed.
