Conjunctival biopsies in gyrate atrophy of the choroid and retina.

The conjunctival biopsy of gyrate atrophy of the choroid and retina displays, besides some atypical changes, the accumulation in the epithelial cells of osmiophilic particles, which are probably lipids and which are also found in the fibroblasts of the conjunctival stroma.

[The sclerocorneal trabeculum following cortisone treatment and perfusion of the anterior chamber with hyaluronidase (author's transl)]. / Aspekte des sklerokornealen Trabekulums nach Kortisonbehandlung und Perfusion der Vorderkammer mit Hyaluronidase.

Following perfusion of the anterior chamber with hyaluronidase, a great reduction in the basic substance of the sclero corneal trabeculum as well as increased activity of the goniocytes were observed with the electron microscope. The opening of the trabecular meshes thus produced constitutes a kind of chemical trabeculectomy, attributable to the depolymerization of the hyaluronates of the basic substance by the hyaluronidase of the goniocytes.