ABSTRACT
In high arterial hypertension conditioned by main renal arteries stenosis of different genesis, 21.1% of patients were found to have a combination of renovascular hypertension with parenchymatous renal diseases, most often chronic pyelonephritis. The incidence of development of the malignant hypertension syndrome in combined lesions was noted to be 1.5 times higher than in isolated renovascular hypertension and makes 38.8% of patients. The described features of the clinical course, laboratory, radiological and radionuclide data as well as morphologic state of kidneys make it possible to distinguish this form of symptomatic hypertension as a special one, that is renovascular-parenchymatous hypertension.
Subject(s)
Hypertension, Renal/etiology , Hypertension, Renovascular/etiology , Chronic Disease , Hemodynamics , Humans , Hypertension, Renovascular/physiopathology , Kidney/physiopathology , Male , Oxygen Consumption , Pyelonephritis/etiology , Pyelonephritis/physiopathology , Renal Circulation , Renin-Angiotensin SystemABSTRACT
Stenosis and thrombosis of the main renal artery were detected in 248 of 867 patients with arterial hypertension (28%). The combination of renal artery stenosis with pyelonephritis was encountered in 19% (46 subjects) of patients with the affected main renal artery. The syndrome of malignant arterial hypertension in the combined affections was diagnosed in 39.1% of patients. The study of the total renal filtration function in combined diseases may be of prognostic importance from the standpoint of normalization of arterial pressure after surgical treatment.
