ABSTRACT
Surgical operation of coronary shunting with resection of postinfarction aneurysm of the left ventricle (PALV) had to be done on 65 patients. Automatic plasmapheresis (AP) and plasmothrombocytopheresis (PTCA) were performed in the reoperation period for transfusion maintenance. The cellular composition of peripheral blood was not changed under the influence of cellular operations with the exception of thrombocytes: after PTCA their content was reliably decreased. AP and PTCA operations in patients with PTLV led to initially increased content of blood fibrinogen, whole protein in 24 hours, but by the time of operation the indices of protein metabolism were stabilized at the initial level. The operations of AP and PTCA were followed by a reliably decreased concentration of cholesterol, beta-lipoproteins and triglycerides that was associated with plasma exfusion. PA and PTCA fulfilled before operation in PALV patients allow both reservation of autologous plasma and thrombocytes and normalization of certain indices of hemostasis.
Subject(s)
Heart Aneurysm/therapy , Homeostasis/physiology , Myocardial Infarction/complications , Plasmapheresis/methods , Plateletpheresis/methods , Ventricular Dysfunction, Left/etiology , Follow-Up Studies , Heart Aneurysm/etiology , Heart Aneurysm/physiopathology , Humans , Myocardial Infarction/physiopathology , Severity of Illness Index , Treatment Outcome , Ventricular Dysfunction, Left/physiopathology , Ventricular Dysfunction, Left/therapyABSTRACT
The article presents results of using the method of intraoperative autotransfusion in surgical treatment of IHD. It was shown that in patients with IHD intraoperative reservation of 400 ml of autoblood at the stage of surgical access (prior to infusion of heparin) during coronary shunting did not lead to disturbances of hemodynamics, gas exchange and oxygen-transporting function of blood. The following transfusion of predonated autoblood at the final stage of operation promotes the early reestablishment of the circulating erythron and allows to reduce the requirement of transfusion of the donor erythrocyte concentrate by 26.1%, and chilled plasma--by more than 1.5 times.
Subject(s)
Blood Transfusion, Autologous , Myocardial Ischemia/surgery , Blood Loss, Surgical , Blood Transfusion, Autologous/methods , Blood Volume , Coronary Artery Bypass , Humans , Intraoperative Care , Postoperative Care , Treatment OutcomeABSTRACT
Effect of in vitro exposure to therapeutic He-Ne laser at a wave-length of 630 nm in two modes, 2 and 6 mWt, on the function of blood cells is studied. Exposure to 6 mWt resulted in spontaneous increase of interleukin-1 production by peripheral blood mononuclears. 2 mWt exposure led to increase of erythrocyte deformability and decrease of their viscosity, whereas 6 mWt exposure did not modify these parameters. Laser-effected changes in the production of other cytokines, primarily interleukins 2, 6, and 8, are a perspective trend of research.
