ABSTRACT
The paper submits the statistical analysis of data on the mortality structure obtained by the experiment with chronic external gamma-irradiation within a wide range of dose rates. The cumulative mortality rate was a function of time. The authors discuss whether the shortening of life span resulting from chronic exposure to gamma-radiation is or is not specific.
Subject(s)
Longevity/radiation effects , Radiation Injuries, Experimental/mortality , Animals , Chronic Disease , Dose-Response Relationship, Radiation , Gamma Rays , Male , Neoplasms, Radiation-Induced/mortality , Rats , Statistics as TopicABSTRACT
Pathoanatomical analysis, carried out after the combined effect of whole-body irradiation and pesticides of different classes over 5 days in doses of 1/4 LD50/30 and 1/4 LD50, respectively, did not exhibit any changes other than those caused by each of the factors applied separately.
Subject(s)
Pesticides/poisoning , Radiation Injuries, Experimental/complications , Animals , Hexachlorocyclohexane/poisoning , Male , Rats , Thiram/poisoning , Trichlorfon/poisoningABSTRACT
Chronic exposure to ionizing radiation at dose-rates of 1.7 to 13.5 cGy/day has some distinctive features among which the development of radiation affection at the dose rate of 13.5 cGy/day is the main one. At lesser dose rates no qualitative changes in the causes of the animals' death were noted while their quantitative relationship was impaired. The increase in the tumor occurrence was registered at the dose-rate of 3.5 cGy/day. The average life of animals in all groups under study was much shorter than in the controls.
Subject(s)
Neoplasms, Radiation-Induced/etiology , Radiation Dosage , Radiation Injuries, Experimental/etiology , Animals , Cesium Radioisotopes , Follow-Up Studies , Gamma Rays , Male , Neoplasms, Radiation-Induced/mortality , Radiation Injuries, Experimental/mortality , Rats , Time Factors , Whole-Body IrradiationABSTRACT
Albino male rats were divided into four groups and exposed to gamma-radiation (137Cs) for 80, 40, 20 and 10 days at dose rates of 0.25, 0.5, 1.0 and 2.0 Gy/day, respectively. The development of lesions and remote aftereffects was shown to depend upon conditions of formation of the absorbed dose. With fractionated irradiation at dose rates above 1.0 Gy/day the dose-rate played a major role in producing the effect.