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BMJ Case Rep ; 12(3)2019 Mar 16.
Article in English | MEDLINE | ID: mdl-30878964

ABSTRACT

Carcinoid tumours have the ability to secrete various peptides and bioamines that lead to carcinoid syndrome manifested as cutaneous flushing, diarrhoea, bronchial constriction and cardiac involvement. The deficiencies of vitamins D and B12 have previously been reported in patients with carcinoid tumours presumably due to chronic diarrhoea associated with the carcinoid syndrome. Herein, we chronicle the case of a patient with opioid use disorder who presented with small bowel obstruction that was found to be caused by a midgut carcinoid tumour. Laboratory studies revealed deficiencies of vitamins D and B12 even though he denied diarrhoea and had no other aetiology of deficiencies of these vitamins. Additionally, this paper presents a review of the published medical literature pertaining to clinical features, diagnostic investigations and treatment of intestinal carcinoid tumours and explores possible explanations for the observed deficiencies in these patients.


Subject(s)
Carcinoma, Neuroendocrine/pathology , Ileal Neoplasms/pathology , Carcinoma, Neuroendocrine/complications , Carcinoma, Neuroendocrine/diagnostic imaging , Carcinoma, Neuroendocrine/surgery , Humans , Ileal Neoplasms/complications , Ileal Neoplasms/diagnostic imaging , Ileal Neoplasms/surgery , Laparotomy , Male , Middle Aged , Opioid-Related Disorders/complications , Vitamin B 12 Deficiency/complications , Vitamin B 12 Deficiency/diagnosis , Vitamin D Deficiency/complications , Vitamin D Deficiency/diagnosis
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