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Ir J Med Sci ; 180(4): 897-900, 2011 Dec.
Article in English | MEDLINE | ID: mdl-19291353

ABSTRACT

Mucinous cystadenomas of the appendix are rare, with significant malignant potential [Lo and Sarr in Hepatogastroenterology 50(50):432-437, 2003]. Carcinoid tumours are similarly uncommon, rarely occurring in Meckel's diverticula but are still the commonest tumour of Meckel's diverticulae [Nies et al. in Dis Colon Rectum 35(6):589-596, 1992; Modlin and Lye in Cancer 97(4):934-959, 2003; Sutter et al. in Schweiz Med Wochenschr Suppl 89:20S-24S, 1997; Weber and McFadden DW in J Clin Gastroenterol 11(6):682-686, 1989]. A 77-year-old woman presented to our clinic with a 6-week history of non-specific lower abdominal pain. A pelvic ultrasound showed an 8 × 3 × 2.5 cm mass in the right iliac fossa. Colonoscopy and CT confirmed this mass and also revealed a left colonic tumor. At laparotomy, three tumours were identified; in the appendix, a Meckel's diverticulum, and the descending colon. A subtotal colectomy and diverticulectomy were performed. Histology confirmed a T3N0 Dukes B colonic adenocarcinoma, a carcinoid of Meckel's diverticulum and a mucinous adenoma of the appendix. The patient is tumor free to date, 5 years after presentation. The presence of three synchronous tumours of different histological origin in the gastrointestinal tract has not previously been described in the literature.


Subject(s)
Adenocarcinoma/pathology , Adenoma/pathology , Carcinoid Tumor/pathology , Intestinal Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Adenocarcinoma/surgery , Adenoma/surgery , Aged , Carcinoid Tumor/surgery , Female , Humans , Intestinal Neoplasms/surgery , Meckel Diverticulum/pathology , Meckel Diverticulum/surgery , Neoplasms, Multiple Primary/surgery
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