ABSTRACT
An account is given in this paper of 6 women aged between 41 and 70 years in whom mesenchymal tumors developed after surgery and postoperative radiotherapy for mammary carcinoma. Malignant fibrous histiocytoma developed in 2 women, five and a half or ten and a half years after primary therapy. Angiosarcoma (Stewart-Treves syndrome) was recorded from another 2 women, three and a half or ten years after primary treatment. One women exhibited a chondrosarcoma, following an interval of six and a half years. Premalignant early phase of Stewart-Treves syndrome was diagnosed, after 8 years, in a woman who was 41 years of age. The criteria for assumption of post-radiogenic secondary tumor, as demanded by Cahan et al. (1948), are discussed in some detail. Its avoidance or early detection is considered to depend on individual, stage-related therapeutic planning and long-term follow-up of patients who had undergone surgery and postoperative radiotherapy for mammary carcinoma.
Subject(s)
Breast Neoplasms/surgery , Carcinoma/surgery , Mesenchymoma/etiology , Neoplasms, Radiation-Induced/etiology , Adult , Aged , Breast Neoplasms/radiotherapy , Carcinoma/radiotherapy , Chondrosarcoma/etiology , Female , Follow-Up Studies , Hemangiosarcoma/etiology , Histiocytoma, Benign Fibrous/etiology , Humans , Middle AgedABSTRACT
Dose distributions of a combination from telecobalt-arc-therapy and afterloading-therapy for radiation therapy of gynecological cancers were calculated, using a computer program developed in our institute. Taking as a basis CT-scans the bone structures were taken into consideration like inhomogeneities. Conclusions about the individual dose on sensitive organs into the irradiated area like bladder and rectum become possible. The influence of changing parameters such like distance of axis of arc-therapy can be shown clearly.
Subject(s)
Brachytherapy , Genital Neoplasms, Female/radiotherapy , Radioisotope Teletherapy , Radiotherapy Planning, Computer-Assisted , Cobalt Radioisotopes/therapeutic use , Female , Genital Neoplasms, Female/diagnostic imaging , Humans , Tomography, X-Ray ComputedABSTRACT
A case of an extragonadal endodermal sinus tumour in a three-year old boy is presented. Complete resection of the retroperitoneal tumour was possible after initial chemotherapy. Combined radio-chemotherapy after tumour removal led to complete remission now lasting for more than 5 years. There was unilateral renal atrophy and diverticulum of the stomach as treatment related complications. The favourable prognosis of this tumour due to intensified treatment is discussed in relation to treatment sequelae. The interdisciplinary approach in treatment of cancer in children is emphasized.
Subject(s)
Mesonephroma/therapy , Retroperitoneal Neoplasms/therapy , Child, Preschool , Combined Modality Therapy , Follow-Up Studies , Humans , Kidney/radiation effects , Kidney Function Tests , Male , Radiation Injuries/etiologyABSTRACT
For use in afterloading therapy there was constructed a special combination consisting of X-ray multiplier and a gynaecological table. Because of the constant magnification of radiographs topometric examinations became easier. Examining the displacement of points of interest when the patient is restored from a lithotomic position into a position with stretched legs we concluded that from the point of view of treatment planning it will be necessary to carry out afterloading irradiation with stretched legs like in the teletherapy. Only in such a way it is possible to calculate a common dose distribution of teletherapy and afterloading therapy.
Subject(s)
Brachytherapy/methods , Genital Neoplasms, Female/radiotherapy , Posture , Brachytherapy/instrumentation , Female , HumansSubject(s)
Breast Neoplasms/radiotherapy , Cobalt Radioisotopes/therapeutic use , Computers , Microcomputers , Radioisotope Teletherapy/instrumentation , Radiotherapy Planning, Computer-Assisted , Radiotherapy, Computer-Assisted , Breast Neoplasms/surgery , Combined Modality Therapy , Female , HumansABSTRACT
A systematic screening-programme for tumor recurrence diagnosis was carried out in 773 patients with cervical or endometrial carcinomas. In comparison with two other patient groups in this patients an earlier diagnosis of tumor recurrences was possible and more relapses were detected in the subclinically symptomless phase. Considering the primary therapy a practicable scheme for diagnosis is proposed.
