1.
Org Biomol Chem
; 9(1): 136-40, 2011 Jan 07.
Article
in English
| MEDLINE
| ID: mdl-21103523
ABSTRACT
The Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.
Subject(s)
Esters/chemistry , Phosphines/chemistry , Sulfhydryl Compounds/chemistry , Fluorine Radioisotopes/chemistry , Molecular Structure
2.
Angew Chem Int Ed Engl
; 48(3): 586-9, 2009.
Article
in English
| MEDLINE
| ID: mdl-19053117
3.
Chem Commun (Camb)
; (31): 3622-4, 2008 Aug 21.
Article
in English
| MEDLINE
| ID: mdl-18665278
ABSTRACT
A novel fluorous tagging-detagging strategy has been developed featuring a fluorination as the detagging process; fluorous allylsilanes were prepared by cross-metathesis and subsequently subjected to electrophilic fluorodesilylation; Selectfluor was used as the detagging reagent; the resulting allylic fluorides were successfully purified by fluorous solid phase extraction.