ABSTRACT
Laboratory testing of donor blood is the key point in prevention of hemotransmissive syphilis. The probability of using diagnostic EIA kit RecombiBest antipallidum-strip (AO Vektor-Best, Novosibirsk) is assessed. Ninety-two donor sera were tested. For assessing the sensitivity of the test system, 11 sera of syphilis patients were titrated by double dilutions 1:10 to 1:1280 for each strip. In parallel with this, antibodies to T. pallidum were assessed in the precipitation microtest. EIA proved to be not only highly specific, but more sensitive than precipitation microtest. Antibodies to T. pallidum are detected by EIA in serum dilutions at least two times higher than the minimal titers in the precipitation test. Thus, the above diagnostic kit is recommended for screening of donors of blood and its components.
Subject(s)
Blood Donors , Syphilis Serodiagnosis/methods , Antibodies, Bacterial/blood , Biomarkers/blood , Humans , Immunoenzyme Techniques/instrumentation , Immunoenzyme Techniques/statistics & numerical data , Reagent Kits, Diagnostic/statistics & numerical data , Sensitivity and Specificity , Syphilis Serodiagnosis/instrumentation , Syphilis Serodiagnosis/statistics & numerical data , Treponema pallidum/immunologyABSTRACT
The Avicenna test system (St. Petersburg) for detecting antibodies to hepatitis C is assessed. Two-hundred and ten sera with increased SGPT activity and 73 samples seropositive in screening by the Aquapast test system (St. Petersburg) were examined. Avicenna system with 3 synthetic peptides as the test objects is characterized by a higher sensitivity and specificity and is recommended for practical use at blood service institutions.
Subject(s)
Blood Donors , Hepatitis C Antibodies/blood , Adolescent , Adult , Alanine Transaminase/blood , Humans , Immunoenzyme Techniques , Male , Sensitivity and SpecificityABSTRACT
In the work the factors, rendering essential influence on organization of donorship in modern army conditions are systematized. The organization of donorship should be connected to functioning of territorial system of medical maintenance of the Armed Forces of RF. It assumes presence of four organizational levels: central, district, zone and garrison. Perfecting the system of organization of donorship, we should be guided by the following conducting principles: maximum maintenance of safety of donorship; wide introduction of a method of plasmacytopheresis in work of establishments and subdivisions of blood supply service; organization of autodonorship and quota of the donors of an emergency reserve in each military-medical establishment; reliable maintenance of revealing of markers of hemotransmissible infections at inspection of the donors.
